Tetracosanol

Flash point

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

flash point of flammable liquids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2009-01-22

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods with acceptable restrictions

Remarks:

Test procedure in accordance with national standard methods (ISO) without GLP.

Qualifier:

according to guideline

Guideline:

ISO No., other: ISO 2592

Deviations:

not specified

GLP compliance:

no

Type of method:

open cup

Flash point apparatus:

other: Cleveland open cup

Key result

Flash point:

218 °C

Atm. press.:

1 005 mBar

Calibration

Date: 28.09.2009

Operator: J. Wolter

reference material: Petroleum

Lot no. of reference material: 1029

flash point of reference material (theory) in °C: 224,1 +/- 12

flash point of reference material (experimental) in °C: 215,0

Measurement

(triple determination)

temperature of first ignition trial in °C: 196 / 196 / 196

ignitions/min: 5-6 / 5-6 / 5-6

ignation temperature in °C: 216 / 219 / 219

atmospheric pressure in mbar: 1005 / 1005 / 1005

Conclusions:

A Flash point value of 218°C at atmospheric pressure was obtained for the substance using a relevant test method. The result is considered to be reliable.

Executive summary:

The Flash point of Tetracosanol was determined according to ISO 2592. The flash point is measured to be 218 °C at atmospheric pressure.

Reference 2

Endpoint:

flash point of flammable liquids

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2009-11-06

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

test procedure in accordance with national standard methods with acceptable restrictions

Remarks:

Test procedure in accordance with national standard methods (ASTM) without GLP.

Qualifier:

according to guideline

Guideline:

ASTM D93 (Standard test methods for flash point by pensky-martens closed cup tester)

Version / remarks:

2002. Remark: ASTM-D93

Deviations:

no

GLP compliance:

no

Type of method:

non-equilibrium method closed cup

Flash point apparatus:

Pensky-Martens apparatus

Key result

Flash point:

210 °C

Atm. press.:

102.3 kPa

Measurement parameters

Rotation Speed of the Sample Stirrer:100 rpm

Expected Flash Point of Sample: 227.0°C

Measurement

(repeat determination)

Temperature of Initial Ignition Source Application:170.0°C / 170.0°C

Atmospheric Pressure:102.8 kPa / 102.3 kPa

Flash Point (Uncorrected):179.4°C / 176.7°C

Flash Point (Corrected):179.0°C / 176.5°C

Interpretation of results:

GHS criteria not met

Conclusions:

A flash point value of 210°C at standard pressure was determined for the substance using a relevant test method. The result is considered to be reliable.

Executive summary:

Docosan-1 -ol was determined according ASTM D 93. The Flash point was determined to be 210°C at atmospheric pressure.

Reference 3

Endpoint:

flash point of flammable liquids

Type of information:

read-across from supporting substance (structural analogue or surrogate)

Adequacy of study:

supporting study

Justification for type of information:

1. HYPOTHESIS FOR THE CATEGORY APPROACH
The hypothesis is that the category members have similar structures, and flammability properties which vary across the category, forming a regular pattern (Scenario 4 in the RAAF). The interpretation of the observed trends of variation of this property across the category is discussed in the endpoint summary.

2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)
Please refer to the test material identity information within each endpoint study record.
The long chain linear aliphatic alcohol Category has at its centre an homologous series of increasing carbon chain length alcohols. The category members are structurally very similar. They are all primary aliphatic alcohols with no other functional groups. The category members are linear or contain a single short-chain side-branch at the 2-position in the alkyl chain, which does not significantly affect the properties (‘essentially linear’). The category members have saturated alkyl chains or contain a small proportion of naturally-occurring unsaturation(s) which does not significantly affect the properties. The branched and unsaturated structures are considered to have such similar properties that their inclusion in the category is well justified.
Impurities: Linear and/or ‘essentially linear’ long chain aliphatic alcohols of other chain lengths may be present. These are not expected to contribute significantly to the properties in respect of this endpoint due to predictable trends (see point 3).
There are no impurities present at above 1% which are not category members or which would affect the properties of the substance.

3. CATEGORY JUSTIFICATION
The category members are structurally very similar (see point 2) and are biochemically very similar. The metabolic synthesis and degradation pathways are well established. This Category is associated with a consistency and predictability in the physicochemical, environmental, and toxicological property data across its members.
The context of trends observed in this property across the range of chain lengths covered by this Category is described in the Endpoint Summary and in the Category Report attached in Section 13. In this registration, the information requirement is interpolated based on read-across from docoscanol, the neighbouring member of the category with slightly shorter chain length (alkyl chain length of 22), for which the comparability is strongest (in view of the similar physico-chemical properties of the source and target substances as well as similar position in terms of category trends).

4. DATA MATRIX
A data matrix for the C6-24 alcohols Category is attached in Section 13.

Reason / purpose for cross-reference:

read-across: supporting information

Flash point:

> 210 °C

Atm. press.:

1 013 hPa

Remarks on result:

other:

Remarks:

In the closest available analogue with reliable data from a closed-cup method, a flash point of 210°C at 1013 hPa was determined for docosan-1-ol using a non-equilibrium closed-cup method in accordance with ASTM-D93. Hence a similar or higher value can be expected for tetracosan-1-ol.

Interpretation of results:

GHS criteria not met

Description of key information

The flash point of tetracosan-1-ol is 218°C using an open-cup method.

Key value for chemical safety assessment

Flash point at 101 325 Pa:

218 °C

Additional information

The open cup flash point of 218°C was determined in a reliable study.

No closed cup result is reported for tetracosan-1-ol, but available reliable data from alcohols of similar chain length clearly suggest that the result would not be expected to be below ca. 200°C. Together these form a reliable weight of evidence within the Category context particularly in view that the flash point temperature tends to increase as chain length increases (see below). In the closest available analogue with reliable data from a closed-cup method, a flash point of 210°C at 1013 hPa was determined for docosan-1-ol using a non-equilibrium closed-cup method in accordance with ASTM-D93.

Discussion of trends in the Category of C6-24 linear and essentially-linear aliphatic alcohols:

The flash point of Category substances follow a predictable trend of increasing flash point temperature with increasing chain length together with increasing boiling point and decreasing vapour pressure.