Guaiacol

Guidance on Safe Use

First-aid measures

General advice:

-       First aider needs to protect himself.

-       Show the safety data sheet to the doctor in attendance.

-       Place affected clothing in a sealed bag for subsequent decontamination.

-       Use appropriate protective equipment when treating a contaminated person.

Following inhalation:

-       Quickly move the person away from the contaminated area. Make the affected person rest.

-       Immediate medical attention is required.

Following skin contact:

-       Take off contaminated clothing and shoes immediately.

-       Wash off immediately with plenty of water for at least 15 minutes.

-       Immediate medical attention is required.

-       Be aware to maintain life support if necessary.

Following eye contact:

-       Rinse immediately with plenty of water, also under the eyelids, for at least 15 minutes.

-       Keep eye wide open while rinsing.

-       Always obtain medical advice, even if there are no symptoms.

Following ingestion:

-       Do NOT induce vomiting.

-       Immediate medical attention is required.

-       Do not give anything to drink.

Most important symptoms and effects:

In case of skin contact

Symptoms

-       Convulsions

-       Coma

Effects

-       Specific serious local burns will depend on the concentration, contact duration and individual response, systemic poisoning  will mainly result in neurological disorders (convulsion, coma), kidney and liver damage. Fatal injury has been described when 80% to 100% concentration solutions have been in skin contact from 5 to 30 minutes.

In case of eye contact

Symptoms

-       Blindness

Effects

-       Eyes splashes can lead to severe cornea destruction.

In case of inhalation

Symptoms

-       Convulsions

-       Coma

Effects

-       Inhalation can lead to local effects in the respiratory tract, from irritation, lung oedema and neurological disorders.

In case of ingestion

Symptoms

-       Convulsions

-       Cardiac irregularities

-       cytolysis

-       tubular necrosis

-       Coma

Effects

-       Ingestion can lead to neurological disorders, digestive tract corrosion, cardiovascular symptoms (heart rhythm disorders), liver (cytolysis) and kidney (tubular necrosis) damage.

Indication of any immediate medical attention and special treatment needed

Notes to physician

- Read instructions before using.

- PVP/IPA can also be used preferably in case of large exposure alternatively.

- In case of limited exposure, PEG 3550 could be used.

Fire-fighting measures

Suitable extinguishing media:

-       Water spray

-       powder

-       Carbon dioxide (CO2)

-       Foam

-       Use extinguishing measures that are appropriate to local circumstances and the surrounding environment.

Unsuitable extinguishing media

-       High volume water jet

Advice for fire fighter:

Special protective equipment for firefighters

-       Special protective equipment for firefighters

-       Self-contained breathing apparatus.

Specific fire fighting methods

-       Use appropriate means for fighting adjacent fires.

-       Evacuate personnel to safe areas.

-       Cool containers/tanks with water spray.

-       Collect contaminated fire extinguishing water separately. This must not be discharged into drains.

Special hazards

-       Harmful or toxic vapours are released.

-       Combustible solid.

-       Risk of dust explosion.

Accidental release measures

Personal precautions:

-       Avoid contact with the skin and the eyes.

-       Remove all sources of ignition.

-       Do not breathe vapour.

-       Mark the contaminated area with signs and prevent access to unauthorized personnel.

-       Signal word

-       Ventilate the area.

Personal protective equipment

-       Boots

-       Safety glasses

Environmental precautions:

-       Do not allow uncontrolled discharge of product into the environment.

-       Dam up.

Methods and material for containment and cleaning up:

Recovery

-       Keep in properly labelled containers.

-       with a closing device.

Decontamination/cleaning

-       Wash off with plenty of water.

-       Recover the cleaning water for subsequent disposal.

Disposal

-       Treat recovered material as described in the section "Disposal considerations".

Handling and storage

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each Manufacturing site.

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Manufacturer/User of the Registrant’s intermediate.

Precautions for safe handling:

-       When transferring from one container to another apply earthing measures and use conductive hose material.

-       Avoid the formation or spread of mists in the atmosphere.

Hygiene measures

-       Handle in accordance with good industrial hygiene and safety practice.

-       Wash hands before breaks and at the end of workday.

-       When using do not eat, drink or smoke.

-       Eye wash bottles or eye wash stations in compliance with applicable standards.

-       Ensure that eyewash stations and safety showers are close to the workstation location.

Conditions for safe storage

-       The floor of the depot should be impermeable and designed to form a water-tight basin.

-       Keep away from open flames, hot surfaces and sources of ignition.

-       Keep in a cool, well-ventilated place.

-       Keep away from: Strong oxidizing agents

Packaging material:

Suitable material

-       glass

-       Polyethylene

-       Polyethylene liner in a stainless steel drum.

Unsuitable material

-       Aluminium and its alloys.

Transport information

Land transport (UN RTDG/ADR/RID)

UN number:

NOT restricted

Shipping

Labels:

NOT restricted

SpecialProvisions

Inland waterway transport (UN RTDG/ADN(R))

UN number:

NOT restricted

Shipping

Labels:

NOT restricted

Remarks

Marine transport (UN RTDG/IMDG)

UN number:

NOT restricted

Shipping information

Proper shipping name and description:

NOT restricted

Chemical name:

NOT restricted

Labels:

NOT restricted

Remarks

Air transport (UN RTDG/ICAO/IATA)

UN number:

NOT restricted

Shipping information

Proper shipping name and description:

NOT restricted

Chemical name:

NOT restricted

Labels:

NOT restricted

Remarks

SpecialProvisions

Exposure controls / personal protection

This substance is handled under Strictly Controlled Conditions in accordance with REACH regulation Article 17(3) for on-site isolated intermediates and, in case the substance is transported to other sites for further processing, the substance should be handled at these sites under the Strictly Controlled Conditions as specified in REACH regulation Article 18(4). Site documentation to support safe handling arrangements including the selection of engineering, administrative and personal protective equipment controls in accordance with risk-based management systems is available at each Manufacturing site.

Written confirmation of application of Strictly Controlled Conditions has been received from every affected Distributor and Downstream Manufacturer/User of the Registrant’s intermediate.

Exposure measures - Engineering measures

-       Provide appropriate exhaust ventilation at places where dust is formed.

-       Apply technical measures to comply with the occupational exposure limits.

Exposure measures -Personal protection

-       The protective equipment must be selected in accordance with current CEN standards and in cooperation with the supplier of the protective equipment.

-       Selection of appropriate personal protective equipment should be based on an evaluation of the performance characteristics of the protective equipment relative to the task(s) to be performed, conditions present, duration of use, and the potential hazards and/or risks that may occur during use.

Hand protection

-       Take note of the information given by the producer concerning permeability and break through times, and of special workplace conditions (mechanical strain, duration of contact).

-       Impervious gloves

-       The selected protective gloves have to satisfy the specifications of Regulation (EU) 2016/425 and the standard EN 374 derived from it.

Feet protection

-       Boots

Body protection

-       Dust impervious protective suit

-       Change working clothes after each workshift.

-       Contaminated work clothing should not be allowed out of the workplace.

Eye protection

-       Dust proof goggles, if dusty.

-       Tightly fitting safety goggles

-       Eye wash bottles or eye wash stations in compliance with applicable standards.

Respiratory protection

-       Keep in a well-ventilated place.

-       Use the indicated respiratory protection if the occupational exposure limit is exceeded and/or in case of product release (dust).

Hygiene measures

-       Handle in accordance with good industrial hygiene and safety practice.

-       Wash hands before breaks and at the end of workday.

-       When using do not eat, drink or smoke.

-       Eye wash bottles or eye wash stations in compliance with applicable standards.

-       Ensure that eyewash stations and safety showers are close to the workstation location.

Environmental exposure controls

-       Dispose of rinse water in accordance with local and national regulations.

-       Do not allow uncontrolled discharge of product into the environment.

-       Dam up.

Stability and reactivity

Reactivity

-       No hazards to be specially mentioned.

-       Not classified as a reactivity hazard.

Chemical stability

-       Stable under recommended storage conditions.

Possibility of hazardous reactions

-       Hazardous polymerisation does not occur.

Conditions to avoid

-       Heat, flames and sparks.

-       Static electricity

-       Avoid dust formation.

Incompatible materials

                 -    Bases

                 -    Strong oxidizing agents

Hazardous decomposition products                

                -    On combustion or on thermal decomposition (pyrolysis) releases:

                -    Toxic Gas

                -    (Phenol).

                -    (Carbon oxides (CO + CO2)).

Disposal considerations

Product Disposal - Prohibition:

- Avoid release to the environment.

- Must be incinerated in a suitable incineration plant holding a permit delivered by the competent authorities.

Measure for waste avoidance or recovery:

-Do not dispose of with domestic refuse.