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Annexe III – inventaire

Annexe III – inventaire

L'ECHA a établi un inventaire de substances susceptibles de répondre aux critères de l'annexe III du règlement REACH. L'objectif est d'aider les déclarants à déterminer s'ils peuvent bénéficier d'exigences d'information réduites ou s'ils doivent fournir l'ensemble des informations requises au titre de l'annexe VII.

L'inventaire a été établi à partir de bases de données publiques comprenant des données expérimentales et à l'aide de résultats de modèles R(Q)SA. Les indications de propriétés toxicologiques ou écotoxicologiques dangereuses, associées aux informations sur les utilisations et aux autres informations pertinentes disponibles, doivent être comparées aux critères de l'annexe III.

Le fait qu'une substance ne figure pas dans cette liste ne signifie pas nécessairement que les critères de l'annexe III ne sont pas remplis. Parallèlement, lorsqu'une substance figure dans l'inventaire, une déclarant peut continuer à bénéficier d'exigences d'information réduites, si cela est justifié.

Veuillez noter que l'inventaire n'est pas un outil de classification; il ne présente que des éléments qui suscitent des préoccupations. Par exemple, le fait qu'une substance soit indiquée comme «Suspectée d'être mutagène» ne signifie pas que l'ECHA la considère comme une substance classée comme mutagène. Il convient de prendre en considération tous les éléments de preuve avant de conclure à la nécessité d'une classification.

γ-HCH or γ-BHC

EC / List no.: 200-401-2 CAS no.: 58-89-9
Information source
# Harmonised classification for acute toxicity: The substance is listed in Annex VI of CLP as: Acute Tox. 3; The substance is listed in Annex VI of CLP as: Acute Tox. 4 # Harmonised classification for aquatic toxicity: The substance is listed in Annex VI of CLP as: Aquatic Acute 1; The substance is listed in Annex VI of CLP as: Aquatic Chronic 1 # Harmonised classification for effects on or via lactation: The substance is listed in Annex VI of CLP as: Effects on or via lactation # Harmonised classification for specific target organ toxicity: The substance is listed in Annex VI of CLP as: STOT RE 2 # Suspected bioaccumulative: Bioaccumulation Canada database in the Toolbox reports at least one value above the B threshold of 2,000 L/Kg (3.3 log units) # Suspected carcinogen: The Toolbox profiler 'Carcinogenicity (genotox and nongenotox) alerts by ISS' gives an alert for carcinogenicity; CAESAR Carcinogenicity model in VEGA (Q)SAR platform predicts that the chemical is Carcinogen (EXPERIMENTAL value); ISS Carcinogenicity model in VEGA (Q)SAR platform predicts that the chemical is Carcinogen (EXPERIMENTAL value); IARC monographs classified the substance as carcinogenic or probably/possibly carcinogenic; carcinogen according to ISSCAN; reasonably anticipated to be a human carcinogen according to NTP 13th RoC # Suspected hazardous to the aquatic environment: EPA Daphnia Magna toxicity model in VEGA (Q)SAR platform predicts that the chemical has a 48h EC50 of 1.79 mg/L (EXPERIMENTAL value); Fathead Minnow toxicity model (EPA) in VEGA (Q)SAR platform predicts that the chemical has a 96h LC50 of 0.0713 mg/L (EXPERIMENTAL value); Fish toxicity classification (SarPy/IRFMN) model in VEGA (Q)SAR platform predicts that the chemical is 'Toxic-3 (between 10 and 100 mg/l) (good reliability)'; Fish Acute Toxicity model (KNN/Read-Across) in VEGA (Q)SAR platform predicts that the chemical has a 96h LC50 of 18.34 mg/L (good reliability);The Danish QSAR database contains information indicating that the substance has a 96h LC50 to fish of 2.24 mg/L; The Danish QSAR database contains information indicating that the substance has a 48h EC50 to Daphnia of 1.57 mg/L; The Danish QSAR database contains information indicating that the substance has a 96h EC50 to green algae of 2.76 mg/L # Suspected mutagen: SARPY Mutagenicity model in VEGA (Q)SAR platform predicts that the chemical is NON-Mutagen (EXPERIMENTAL value); equivocal mutagenicity data according to ISSSTY # Suspected persistent in the environment: Ready biodegradability model (IRFMN) in VEGA (Q)SAR platform predicts that the chemical is NON Readily Biodegradable (moderate reliability); Soil OASIS database in the Toolbox contains at least one experimental data from biodegradation in soil test reporting a value equal or greater than 120 days;The Danish QSAR database contains information indicating that the substance is predicted as non readily biodegradable # Suspected skin irritant: The Danish QSAR database contains information indicating that the substance is predicted as skin irritant # Suspected toxic for reproduction: The Toolbox profiler 'DART scheme v.1.0' gives an alert for toxicity to reproduction;Developmental/Reproductive Toxicity library (PG) in VEGA (Q)SAR platform predicts that the chemical is Toxicant (moderate reliability)

Download the full Annex III Inventory

You can download the full Annex III inventory as XLS format.

Download Annex III Inventory

 

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