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EC number: 202-635-0 | CAS number: 98-08-8
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Boiling point
Administrative data
Link to relevant study record(s)
- Endpoint:
- boiling point
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- from 2018-11-22 to 2019-02-04
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 103 (Boiling Point)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.2 (Boiling Temperature)
- Deviations:
- no
- Qualifier:
- according to guideline
- Guideline:
- EPA OPPTS 830.7220 (Boiling Point / Boiling Range)
- Deviations:
- no
- GLP compliance:
- yes (incl. QA statement)
- Type of method:
- differential scanning calorimetry
- Remarks:
- and Capillary method
- Key result
- Boiling pt.:
- 102.9 °C
- Atm. press.:
- >= 99.24 - <= 99.41 kPa
- Decomposition:
- no
- Conclusions:
- The boiling point of the test item was determined with DSC and capillary method to be 102.9 °C at atmospheric pressure.
- Executive summary:
A study was conducted according to OECD TG 103, Regulation (EC) No 440/2008 method A.2 and EPA OPPTS 830.7220 to determine the boiling point of the test item using differential scanning calorimetry. The test item was weighed out into a 40 µL aluminium crucible under an inert atmosphere (nitrogen). Two tests were performed. As reference crucible, an empty aluminium crucible was used. The crucibles were heated from room temperature up to 500 °C at a constant heating rate of 10 °C/min. The appearance of the test item was noted before and after the test. A supplementary test using the capillary method was performed with the test item. A preliminary and a main test using this method were performed. In the DSC measurement the boiling point was determined to be in the range of 86.8 – 100.9 °C (359.9 – 374.0 K) at atmospheric pressure (101.17 kPa). According to the supplementary test with capillary method the boiling point was determined to 102.9 °C (376.1 K) at 99.41 kPa.
Reference
Appearance of the Samples
Before the test the appearance of the test item was colourless liquid. After the experiments the test item was evaporated from the crucible.
Results – DSC method
Using a linear heating rate of 10 °C/min the boiling point of the test item was determined to be in the range of 86.8 – 100.9 °C (359.9 – 374.0 K) at atmospheric pressure (101.17 kPa).
Table 1. Summary of the DSC Test of Test Item
|
Experiment 1 |
Experiment 2 |
Mean |
Onset of effect [°C] |
91.15 |
82.44 |
86.80 |
Endset of effect [°C] |
103.15 |
98.57 |
100.86 |
Supplementary Test – Capillary method
The apparatus was checked with ultrapure water. The literature boiling point of water is 100 °C. The measured value corresponded to the literature value. The boiling point of water was determined to be 100.3 °C (373.5 K). Measured values were determined to be in the required range (literature value ± 0.5 °C).
Capillary method - Preliminary Test
Preliminary test with the test item was performed before the main test.
Table 2. Preliminary Test– capillary method
Start temperature, °C |
Heating rate, °C/min |
Atmospheric pressure, kPa (at the measuring) |
Boiling point, °C |
25 |
5 |
99.56 |
102.3 |
Capillary method – Main test
For the main study the metal block was heated to 92 °C. The capillaries containing the test item were placed into the apparatus and the temperature was raised at 0.5 °C/min heating rate until the boiling temperature was reached. Three tests were carried out. The boiling point was determined to be 102.9 ± 0.57 °C (95 % confidence interval) i.e. 376.1 K. At the end of the measurements the colour of the samples became slightly yellow.
Table 3. Determination of the Boiling Point of the test item by capillary method
Atmospheric pressure, kPa (at the measuring) |
Boiling point, °C (at standard atmospheric pressure) |
99.41 |
102.8 |
99.33 |
103.2 |
99.24 |
102.8 |
Mean: |
102.9 |
RSD (CV %): |
0.2 |
Conf.int. (95 %) |
0.57 |
Description of key information
The boiling point of the test item was determined with DSC and capillary method to be 102.9 °C at atmospheric pressure.
Key value for chemical safety assessment
- Boiling point at 101 325 Pa:
- 102.9 °C
Additional information
A study was conducted according to OECD TG 103, Regulation (EC) No 440/2008 method A.2 and EPA OPPTS 830.7220 to determine the boiling point of the test item using differential scanning calorimetry. The test item was weighed out into a 40 µL aluminium crucible under an inert atmosphere (nitrogen). Two tests were performed. As reference crucible, an empty aluminium crucible was used. The crucibles were heated from room temperature up to 500 °C at a constant heating rate of 10 °C/min. The appearance of the test item was noted before and after the test. A supplementary test using the capillary method was performed with the test item. A preliminary and a main test using this method were performed. In the DSC measurement the boiling point was determined to be in the range of 86.8 – 100.9 °C (359.9 – 374.0 K) at atmospheric pressure (101.17 kPa). According to the supplementary test with capillary method the boiling point was determined to 102.9 °C (376.1 K) at 99.41 kPa.
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