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EC number: 291-350-5 | CAS number: 90387-74-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Biodegradation in water: screening tests
Administrative data
- Endpoint:
- biodegradation in water: ready biodegradability
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 17.12.1998 to 03.02.1999
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- guideline study without detailed documentation
Data source
Reference
- Reference Type:
- study report
- Title:
- Unnamed
- Year:
- 1 999
- Report date:
- 1999
Materials and methods
Test guidelineopen allclose all
- Qualifier:
- according to guideline
- Guideline:
- other: Kanpogyou No. 5, Yakuhatsu No. 615 and 49 Kikyoku No. 392, 1974
- Qualifier:
- equivalent or similar to guideline
- Guideline:
- OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I))
- GLP compliance:
- yes
- Remarks:
- Yokohama Laboratory, Mitsubishi Chemical Safety Institue Ltd. (M.S.I.), 1000 Kamshida-cho, Aoba-ku, Yokohama, Japan
Test material
- Reference substance name:
- Glycine, N-coco acyl derivs., sodium salts
- EC Number:
- 291-350-5
- EC Name:
- Glycine, N-coco acyl derivs., sodium salts
- Cas Number:
- 90387-74-9
- Molecular formula:
- Molecular formula for this UVCB is not available.
- IUPAC Name:
- Glycine, N-coco acyl derivs., sodium salts
Constituent 1
- Specific details on test material used for the study:
- SOURCE OF TEST MATERIAL
- Source and lot/batch No.of test material: Ajinomoto Co., Inc., Tokyo (Japan)//lot No.: 980119
- Expiration date of the lot/batch: not reported (Date of receipt: 10.11.1998)
- Purity test date: not reported
STABILITY AND STORAGE CONDITIONS OF TEST MATERIAL
- Storage condition of test material:not reported (storage stability of test item over the exposure period of the test was proven by IR spectrum)
TREATMENT OF TEST MATERIAL PRIOR TO TESTING
- Treatment of test material prior to testing:no
- Preliminary purification step (if any): no
Study design
- Oxygen conditions:
- aerobic
- Inoculum or test system:
- activated sludge (adaptation not specified)
- Details on inoculum:
- - Source of inoculum/activated sludge (e.g. location, sampling depth, contamination history, procedure): Activated sludge was obtained from the Chemical Biotesting Center, Chemical Inspection and Testing Institute, Japan
- Laboratory culture: yes
- Method of cultivation: not reported
- Storage conditions: not reported
- Storage length: not reported
- Preparation of inoculum for exposure: not reported
- Pretreatment: no
- Concentration of sludge: 30 mg/L
- Duration of test (contact time):
- 28 d
Initial test substance concentration
- Initial conc.:
- 100 mg/L
- Based on:
- test mat.
Parameter followed for biodegradation estimation
- Parameter followed for biodegradation estimation:
- O2 consumption
- Details on study design:
- TEST CONDITIONS
- Composition of medium: not specified
- Additional substrate: no
- Test temperature: 25 +/- 1°C
- pH: at day 28 in test vessels with test item: 7.1-7.3 (pH 6.2 in abiotic control of test item; aniline: pH 7.9)
- pH adjusted: not reported
- Aeration of dilution water: not reported
- Continuous darkness: not reported
- Other: amount of activated sludge in test vessels: 30 mg/L
TEST SYSTEM
- Culturing apparatus: Closed system oxygen consumption measuring apparatus OM-2001 (respirometer)
- Number of culture flasks/concentration: 6
- Method used to create aerobic conditions: not reported
- Measuring equipment: pH meter; TOC analyzer TOC-5000 (Shimadzu Co.); HPLC for measuring the test item concentration in the test bottles at the end of the exposure period
- Test performed in closed vessels: yes
SAMPLING
- Sampling frequency: at day 7, 14, 21, and 28
- Other: after termination of the test, DOC and the residual concentration of test substance in the test solution were determined
CONTROL AND BLANK SYSTEM
- Inoculum blank: performed
- Abiotic sterile control: performed
- Toxicity control: not performed
- Other: activity control performed with reference substance aniline
Reference substance
- Reference substance:
- aniline
- Remarks:
- 100 mg/L
Results and discussion
% Degradationopen allclose all
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 72
- Sampling time:
- 7 d
- Key result
- Parameter:
- % degradation (O2 consumption)
- Value:
- ca. 80
- Sampling time:
- 28 d
- Key result
- Parameter:
- % degradation (DOC removal)
- Value:
- 99
- Sampling time:
- 28 d
- Key result
- Parameter:
- % degradation (test mat. analysis)
- Value:
- > 98
- Sampling time:
- 28 d
BOD5 / COD results
- Results with reference substance:
- Based on BOD measurements, the reference substance aniline was biodegraded by 67% after 7 d.
Applicant's summary and conclusion
- Interpretation of results:
- readily biodegradable
- Conclusions:
- The test item proved to be readily biodegradable: The mean biodegradation of the test item after 28 d was determined to be 80% based on BOD, 99% based on DOC, and >98% based on residual concentration in the test vessels.
- Executive summary:
The ready biodegradation of the the test item was investigated in a study conducted in accordance with the Test Method Relating to New Chemical Substances (Kanpogyou No. 5, Yakuhatsu No. 615 and 49 Kikyoku No. 392, 1974) as required by the Chemical Substances Control Law of Japan. The test procedure followed is equivalent or similar to OECD Guideline 301C (Ready Biodegradability: Modified MITI Test (I)). The test item (100 mg/L) was inoculated with activated sludge (30 mg/L) for 28 d and the degradation of the test item was determined by measurement of oxygen consumption BOD, DOC and residual test item concentration in the test vessels at the end of the test. Inoculum blank, abiotic control and procedural/functional control with the reference substance aniline (100 mg/L) were performed.
This study is regarded as reliable with restrictions due to missing informations in respect to e.g. origin of activated sludge, composition of basal medium etc..
The test item proved to be readily biodegradable ( 80% based on BOD, 99% based on DOC, and >98% based on residual concentration in the test vessels after 28 d of incubation at test substance concentrations of 100 mg/L). The functional control aniline reached the pass level > 60% after 7 d.
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