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EC number: 215-684-8 | CAS number: 1344-00-9
- Life Cycle description
- Uses advised against
- Endpoint summary
- Appearance / physical state / colour
- Melting point / freezing point
- Boiling point
- Density
- Particle size distribution (Granulometry)
- Vapour pressure
- Partition coefficient
- Water solubility
- Solubility in organic solvents / fat solubility
- Surface tension
- Flash point
- Auto flammability
- Flammability
- Explosiveness
- Oxidising properties
- Oxidation reduction potential
- Stability in organic solvents and identity of relevant degradation products
- Storage stability and reactivity towards container material
- Stability: thermal, sunlight, metals
- pH
- Dissociation constant
- Viscosity
- Additional physico-chemical information
- Additional physico-chemical properties of nanomaterials
- Nanomaterial agglomeration / aggregation
- Nanomaterial crystalline phase
- Nanomaterial crystallite and grain size
- Nanomaterial aspect ratio / shape
- Nanomaterial specific surface area
- Nanomaterial Zeta potential
- Nanomaterial surface chemistry
- Nanomaterial dustiness
- Nanomaterial porosity
- Nanomaterial pour density
- Nanomaterial photocatalytic activity
- Nanomaterial radical formation potential
- Nanomaterial catalytic activity
- Endpoint summary
- Stability
- Biodegradation
- Bioaccumulation
- Transport and distribution
- Environmental data
- Additional information on environmental fate and behaviour
- Ecotoxicological Summary
- Aquatic toxicity
- Endpoint summary
- Short-term toxicity to fish
- Long-term toxicity to fish
- Short-term toxicity to aquatic invertebrates
- Long-term toxicity to aquatic invertebrates
- Toxicity to aquatic algae and cyanobacteria
- Toxicity to aquatic plants other than algae
- Toxicity to microorganisms
- Endocrine disrupter testing in aquatic vertebrates – in vivo
- Toxicity to other aquatic organisms
- Sediment toxicity
- Terrestrial toxicity
- Biological effects monitoring
- Biotransformation and kinetics
- Additional ecotoxological information
- Toxicological Summary
- Toxicokinetics, metabolism and distribution
- Acute Toxicity
- Irritation / corrosion
- Sensitisation
- Repeated dose toxicity
- Genetic toxicity
- Carcinogenicity
- Toxicity to reproduction
- Specific investigations
- Exposure related observations in humans
- Toxic effects on livestock and pets
- Additional toxicological data
Short-term toxicity to fish
Administrative data
Link to relevant study record(s)
- Endpoint:
- short-term toxicity to fish
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Study period:
- 26 Oct. - 31 Oct. 1998
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP guideline study
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 203 (Fish, Acute Toxicity Test)
- GLP compliance:
- yes (incl. QA statement)
- Analytical monitoring:
- no
- Vehicle:
- no
- Details on test solutions:
- PREPARATION AND APPLICATION OF TEST SOLUTION (especially for difficult test substances)
- Method: Water extract (water-accommodated fraction, WAF) by stirring corresponding suspensions for 24 h at 25 °C
with subsequent filtration (paper) of the suspensions. Test solutions were then adjusted to pH 7.00.
- Differential loading: yes, 100, 1000, and 10,000 mg/L
- Controls: yes, untreated
- Chemical name of vehicle (organic solvent, emulsifier or dispersant): no
- Evidence of undissolved material (e.g. precipitate, surface film, etc): no data - Test organisms (species):
- Danio rerio (previous name: Brachydanio rerio)
- Details on test organisms:
- TEST ORGANISM
- Common name: Zebra fish
- Strain: --
- Source: Aquafarm Ryba, D-27391 Zeven/Germany
- Age at study initiation (mean and range, SD):
- Length at study initiation (length definition, mean, range and SD): ~3 cm
- Weight at study initiation (mean and range, SD): no data
- Method of breeding:
- Feeding during test: no
ACCLIMATION
- Acclimation period:
- Acclimation conditions (same as test or not):
- Type and amount of food:
- Feeding frequency:
- Health during acclimation (any mortality observed):
QUARANTINE (wild caught)
- Duration:
- Health/mortality: - Test type:
- static
- Water media type:
- freshwater
- Limit test:
- yes
- Total exposure duration:
- 96 h
- Post exposure observation period:
- none
- Hardness:
- no data
- Test temperature:
- 24.9 - 25.1 °C
- pH:
- 7.0 - 8.4
- Dissolved oxygen:
- 7.2 - 8.0 mg O2/L
- Salinity:
- no data
- Nominal and measured concentrations:
- Loadings: 10,000 mg/L (main test)
0, 100, 1000, and 10,000 mg/L (range finding) - Details on test conditions:
- TEST SYSTEM
- Test vessel: aquarium
- Type: open
- Material, size, headspace, fill volume: 5-L volume, no further data
- Aeration: yes
- Renewal rate of test solution (frequency/flow rate): no
- No. of organisms per vessel: no data
- No. of animals per test concentration: 3 fish for 100 and 1000 mg/L, 7 fish for 10,000 mg/L
- No. of vessels per concentration (replicates):
- No. of vessels per control (replicates):
- No. of vessels per vehicle control (replicates): not relevant
- Biomass loading rate: no data
TEST MEDIUM / WATER PARAMETERS
- Source/preparation of dilution water: tap water (drinking water), corresponding to OECD-203 standard
no data available for the following parameters:
- Total organic carbon:
- Particulate matter:
- Metals:
- Pesticides:
- Chlorine:
- Alkalinity:
- Ca/Mg ratio:
- Conductivity:
- Culture medium different from test medium: no
- Intervals of water quality measurement: monthly
OTHER TEST CONDITIONS
- Adjustment of pH: no
- Photoperiod: no data
- Light intensity: no data
EFFECT PARAMETERS MEASURED (with observation intervals if applicable) : behaviour, mortality
TEST CONCENTRATIONS
- Spacing factor for test concentrations: 10
- Range finding study: conducted with the highest loading as limit test
- Key result
- Duration:
- 96 h
- Dose descriptor:
- LC0
- Effect conc.:
- >= 10 000 mg/L
- Nominal / measured:
- nominal
- Remarks on result:
- other: WAF of loading (filtered water extract)
- Details on results:
- No deaths occurred during testing. No particular findings.
- Validity criteria fulfilled:
- yes
Reference
Description of key information
No deaths occurred within 96 hours with the tested nanoform of Silicic acid, aluminum sodium salt (CAS 1344-00-9, NAS). The LC0 was equal or greater than 10000 mg/l after 96 h.
Key value for chemical safety assessment
Additional information
It is assumed that the freshwater results are also applicable to marine life, i.e. no acute aquatic toxicity is expected from exposure to synthetic amorphous Silicic acid, aluminum sodium salt (CAS 1344-00-9, NAS).
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