Substance Information

Web-sisällön esitys

Infocards are automatically generated based on industry data. What is an infocard?

polyhexamethylene; biguanide hydrochloride

Help Substance identity

The ‘Substance identity’ section links substance identification information from all ECHA databases. The substance identifiers displayed in the InfoCard are the substance name, substance identifiers (EC and CAS number) and/or the molecular formula.

Substance identifiers may have been claimed confidential, or may not have been provided, and therefore not displayed.

EC (European Community) number

The EC Number is the numerical identifier for substances in the EC Inventory. The EC Inventory is a combination of three independent European lists of substances from the previous EU chemicals regulatory frameworks (EINECS, ELINCS and the NLP-list). More information about the EC Inventory can be found here.

If the substance was not covered by the EC Inventory, ECHA attributes a list number in the same format, starting with the numbers 6, 7, 8 or 9.

The EC or list number is the primary substance identifier used by ECHA.

CAS (Chemical Abstract Service) registry number

The CAS number is the substance numerical identifier assigned by the Chemical Abstract Service, a division of the American Chemical Society, to substances registered in the CAS registry database. A substance identified primarily by an EC or list number may be linked with more than one CAS number, or with CAS numbers that have become obsolete. In these cases, the preferred CAS number is displayed first and obsolete CAS numbers are displayed in brackets. More information about CAS and the CAS registry can be found here.

Molecular formula

The molecular formula identifies each type of element by its chemical symbol and identifies the number of atoms of each element found in one discrete molecule of the substance. This information is only displayed if the substance is well–defined, if such information is available in ECHA’s database and is it not claimed confidential.

Molecular structure

The molecular structure is based on InChI annotations stored in the ECHA database. The image is a computer–generated visualisation of the InChI2 character string, which is broadly used as an identifier of chemical structures. This information is only displayed if the substance is well-defined, if such information is available in ECHA’s database and is it not claimed confidential.

More help available here.

EC / List no.: 608-723-9

CAS no.: 32289-58-0

Mol. formula: -

No image available
Help Hazard classification and labelling

The ‘Hazard classification and labelling’ section shows the hazards of a substance through a standardised system of statements and pictograms, as has been established under the CLP (Classification Labelling and Packaging) Regulation. The CLP Regulation makes sure that the hazards presented by chemicals are clearly communicated to workers and consumers in the European Union. The CLP Regulation uses the UN Global Harmonised System (GHS) and European Union Specific Hazard Statements (EUH).

This section searches three sources for information (harmonised classification and labelling (CLH), REACH registrations and CLP notifications). The source of the information is mentioned in the introductory sentence of the hazard statements. When information is available in all sources, the first two are displayed as a priority.

Harmonised classification and labelling (CLH)

Harmonised classification and labelling is a legally binding classification and labelling for a substance, agreed at European Community level. Harmonisation is based on the substance‚s physical, toxicological and eco-toxicological hazard assessment.

The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information.

If the substance is covered by more than one CLH entry (e.g. disodium tetraborate EC no. 215–540–4, is covered by three harmonisations: 005–011–00–4; 005–011–01–1 and 005–011–02–9), CLH information cannot be displayed in the InfoCard as the difference between the CLH classifications requires manual interpretation or verification. If a substance is classified under multiple CLH entries, a link to the C&L Inventory is provided to allow users to view CLH information associated with the substance, instead of having the information automatically generated in the InfoCard.

It is possible that a harmonisation is introduced through an amendment to the CLP Regulation. In that case, the ATP (Adaptation to Technical Progress) number is displayed.

More info on CLH can be found here.

Classification and labelling under REACH

If available, additional information on classification and labelling (C&L) is derived from REACH registration dossiers submitted by industry. This information has not been reviewed or verified by ECHA, and may change without prior notice. REACH registration dossiers have greater data requirements (support studies) than notifications under CLP.

Notifications under the Classification Labelling and Packaging (CLP) Regulation

If no EU harmonised classification and labelling exists and the substance was not registered under REACH, information derived from classification and labelling (C&L) notifications to ECHA under CLP Regulation is displayed under this section. These notifications can be provided by manufacturers, importers and downstream users. ECHA maintains the C&L Inventory, but does not review or verify the accuracy of the information.

For readability purposes, only the pictograms, signal words and hazard statements referred in more than 5% of the notifications under CLP are displayed.

Please note:

The purpose of the information provided under this section is to highlight the substance hazardousness in a readable format. It does not represent a new labelling, classification or hazard statement. Other relevant information includes the following:

  • Substances may have impurities and additives that lead to different classifications. However, substance notifications in the InfoCard are aggregated independently of the impurities and additives.
  • Hazard statements were adapted to improve readability and may not correspond textually to the hazard statements codes description in the European Union Specific Hazard Statements (EUH) or the UN Global Harmonised System (GHS).

To see the full list of notified classifications and to get more information on impurities and additives relevant to classification please consult the C&L Inventory.

More information about Classification and Labelling is available in the Regulations section of ECHA website.

More help available here.

GHS05: Corrosive GHS08: Serious Health Hazard GHS07: Health hazard GHS09: Hazardous to the Environment

Danger! According to the harmonised classification and labelling (ATP05) approved by the European Union, this substance causes damage to organs through prolonged or repeated exposure, is very toxic to aquatic life, is very toxic to aquatic life with long lasting effects, is harmful if swallowed, causes serious eye damage, is suspected of causing cancer and may cause an allergic skin reaction.

Help Properties of concern

The ‘Properties of concern’ section shows ECHA-assigned graphical indicators for certain substance properties that are regarded as critical for human health and/or the environment based on the information provided to the Agency. The following properties have been highlighted as critical:

  • C – Carcinogenic (i.e. classified in carcinogenicity categories 1A or 1B). More information about carcinogenicity here.
  • M – Mutagenic (i.e. classified in mutagenicity categories 1A or 1B). More information about mutagenicity here.
  • R – Toxic to teproduction (i.e. classified in reproductive toxicity categories 1A or 1B). More information about reproductive toxicity here.
  • PBT – Persistent, bioaccumulative and toxic (PBT). More information about persistent, bioaccumulative and toxic substances here.
  • Sensitiser – Sensitiser (i.e. classified as respiratory sensitisation and/or skin sensitisation categories 1, 1A or 1B). More information about respiratory sensitiser here and skin sensitiser here.

The substance properties displayed in this section are derived from harmonised classification and labelling (CLH) and/or REACH registered dossier information. In case the substance classification is not harmonised and the substance is not registered the properties are derived from classifications provided in CLP notifications (with the exception of PBT properties, which are only derived from REACH registered dossiers).

More help available here.

  • S
about INFOCARD - Last updated: 15/01/2016 InfoCard

The InfoCard summarises the non-confidential data of a substance held in the databases of the European Chemicals Agency (ECHA). InfoCards are generated automatically based on the data available at the time of generation.

The quality and correctness of the information submitted to ECHA remains the responsibility of the data submitter. The type of uses and classifications may vary between different submissions to ECHA and for a full understanding it is recommended to consult the source data. Information on applicable regulatory frameworks is also automatically generated and may not be complete or up to date. It is the responsibility of the substance manufactures and importers to consult official publications, e.g. the electronic edition of the Official Journal of the European Union.InfoCards are updated when new information is available. The date of the last update corresponds to the publication date of the InfoCard and not necessarily to the date in which the update occurred in the source data.

More help available here.

Help Help

Regulations and regulatory activities

This substance has been found in the following regulatory activities:

Other names

Regulatory process names
  • Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl), hydrochloride (1:?)
  • polyhexamethylene; biguanide hydrochloride
Other names
  • Poly(iminocarbonimidoyliminocarbonimidoylimino-1,6-hexanediyl), hydrochloride
IUPAC names
  • -
  • poly(hexamethylenebiguanide) hydrochloride
  • Polyaminopropyl Biguanide, HCl