Registration Dossier
Registration Dossier
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EC number: 413-110-2 | CAS number: 135861-56-2
Endpoint summary
Administrative data
Description of key information
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (not sensitising)
- Additional information:
A skin sensitisation test was conducted at (Pharmakon Europe, 2001) for T-1540N. The skin sensitisation test was performed by the Buehler method, and according to OECD Test Guideline 406. 20 Guinea pigs were treated dermally with T-1540N in absolute ethanol paste ( test article 0.1% (w/w) suspension in absolute ethanol) at a dose level of 50% (w/w) paste in absolute ethanol. A concurrent control group was exposed to untreated vehicle during the induction phase.
No animals showed signs of sensitisation following the challenge exposure.
Migrated from Short description of key information:
Skin sensitisation, guinea pigs - not sensitising (0 positive responses out of 20 guinea pigs tested).
Justification for classification or non-classification
In a skin sensitisation test conducted in guinea pigs, no animals (out of 20 tested) were found to exhibit signs of sensitisation. On this basis, it is concluded that T-1540N does not meet the criteria for classification as a skin sensitiser.
No data was available regarding respiratory information for T-1540N
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