Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
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EC number: 425-980-0 | CAS number: 129499-78-1
Acute Toxicity: oral
Administrative data
- Endpoint:
- acute toxicity: oral
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- other: GLP complianced.
Data source
Reference
- Reference Type:
- other: Inquiry result from ECHA
- Title:
- Unnamed
- Year:
- 2 013
Materials and methods
Test guideline
- Qualifier:
- according to guideline
- Guideline:
- other: Directive 92/69/CEE, B.1
- GLP compliance:
- yes
- Test type:
- standard acute method
- Limit test:
- no
Test material
- Reference substance name:
- -
- EC Number:
- 425-980-0
- EC Name:
- -
- Cas Number:
- 129499-78-1
- Molecular formula:
- C12H18O11
- IUPAC Name:
- L-Ascorbic acid 2-glucoside
Constituent 1
Test animals
- Species:
- rat
- Strain:
- Sprague-Dawley
- Sex:
- male/female
Administration / exposure
- Vehicle:
- water
- Remarks:
- distilled
Results and discussion
Effect levels
- Sex:
- male/female
- Dose descriptor:
- LD50
- Effect level:
- > 2 000 mg/kg bw
- Mortality:
- Male: 1000mg/kg bw; Number of animals: 5; Number of deaths: 0
Male: 2000mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 1000mg/kg bw; Number of animals: 5; Number of deaths: 0
Female: 2000mg/kg bw; Number of animals: 5; Number of deaths: 0 - Clinical signs:
- Signs of toxicity related ot dose levels:
MORTALITE:
Aucune mortalite pendant l'essai.
SIGNS CLINIQUES:
Des selles molles ont etes observees pendant l'essai.
POIDS CORPORELS:
Aucun changement n'a ete note. - Gross pathology:
- Effects on organs:
Aucun effet sur les organes.
Applicant's summary and conclusion
- Interpretation of results:
- not classified
- Remarks:
- Migrated information Criteria used for interpretation of results: EU
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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