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Diss Factsheets

Physical & Chemical properties

Stability in organic solvents and identity of relevant degradation products

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Administrative data

Link to relevant study record(s)

Description of key information

Substance stable in common organic solvents (excluding DMF) at room temperature (19°C) and in presence of light over 46 days, Mao 1996

Additional information

The stability of 14C-test substance in seven solvents was investigated under two laboratory conditions; ambient temperature light exposed and -20°C in darkness. Organic samples were tested for 46 days, while water samples were tested for 57 days. The findings are summarized as follows:

 

Solvent

Study Duration / days

Room Temperature, light

-20°C, dark

Reagent water

57

Significant degradation

Stable

Acetonitrile

46

Stable

Stable

Methanol

46

Stable

Stable

Acetone

46

Stable

Stable

Ethyl acetate

46

Stable

Stable

Dimethylformaldehyde

46

Minor degradation

Stable

dichloromethane

46

Stable

Stable