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EC number: 700-597-4
CAS number: 1215841-86-3
This study was performed to evaluate the toxicity of trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide
after a repeated administration per inhalation to rats,
according to OECD-Guideline 412/413, 7 September 2009, as far as useful
for a dose range finder study.
The used dust concentration of the high dose group, 1.03 mg/L, was the
highest technically feasible dust concentration. Nevertheless no toxic
effect was observed in this study after a two week exposure to this
dust. The body weight, the feed consumption, the behaviour, and selected
organ weights were not changed in the exposed groups.
The No-observed-effect-level (NOEL) of trans-N1,N1,N4,N4-Tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide
dust was therefore larger than 1.03 mg/L for rats after
repeated exposure via inhalation for two weeks.
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