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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

According to a Mackay Level I model calculation, the main target compartment for trans-N1,N1,N4,N4-tetrakis(2-hydroxyethyl)-1,4-cyclohexanedicarboxamide will be the hydrosphere (99.999 %). The calculated Henry’s Law constant of 0.0000006 Pa m³/mol at 20 °C indicates very low volatility of trans-N1,N1,N4,N4-tetrakis(2-hydroxyethyl)-1,4-cyclohexanedicarboxamide from surface waters. With a Koc of 0.5 l/kg, there is no relevant sorption potential of the substance to soil or sediment organic matter (Blume scale).


The QSAR calculated rate constant for the OH sensitized photodegradation of N1,N1,N4,N4-tetrakis(2-hydroxyethyl)1,4-cyclohexanedicarboxamide is approximately 87.8E-12 cm3/(molecule * s). At 500,000 OH radicals / cm3 (typical for central Europe), this corresponds to a half-life of 4.4 hours (24 hour-days). Hydrolysis is very slow under environmental conditions. While no ready biodegradation was observed in a manometric respirometry test, degradation rates up to 20% indicate a potential for biodegradation, which is expected to be the predominant way of removal from the environment. The partition coefficient 1-octanol/water was determined as log Kow = -1.32 at 20.6 °C, indicating negligible potential for bioaccumulation.