Registration Dossier

Ecotoxicological information

Endpoint summary

Administrative data

Description of key information

The toxicity of m-cresol to lettuce seedlings (Lactuca sativa) was determined according to OECD Guideline 208 in soil. The EC50 was 69 mg/kg soil d.w. after 7 d and 96 mg/kg soil d.w. after 14 d, representing the most sensitive value.

No data on other terrestrial organisms available. Results with Lactuca sativa were used to derive PNEC soil and to conduct risk-assessment.

Additional information

Data on the toxicity to terrestrial plants are available for constituents of Tar acids, Xylenol fraction (CAS 84989-06-0), namely o-, m-, and p-cresol. These data are used to determine the hazard of Tar acids, Xylenol fraction (CAS 84989-06-0) by applying a weight of evidence and an analogue read-across approach. The studies were conducted with seedlings of Lactuca sativa. A worst-case scenario is followed, i.e. for assessment purposes the most sensitive values are considered. For details on the read-across approach please refer to the analogue justification provided in IUCLID section 13.

The toxicity of m-cresol to lettuce seedlings (Lactuca sativa) was determined according to OECD Guideline 208 in soil. The EC50 was 69 mg/kg soil d.w. after 7 d and 96 mg/kg soil d.w. after 14 d, representing the most sensitive value.

Data on other terrestrial organisms are not available and endpoints are waived based on the outcome of the risk assessment conducted and the Integrated Testing Strategy for toxicity to sediment (ECHA, 2017; Endpoint specific guidance, Chapter R.7c, Section 7.11.6).