2-hydroxy-3-propyl-2H-furan-5-one

Boiling point

Administrative data

Endpoint:

boiling point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

31 July 2018 - 19 April 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Cross-reference

Reason / purpose for cross-reference:

reference to same study

Reference

Endpoint:

melting point/freezing point

Type of information:

experimental study

Adequacy of study:

key study

Study period:

31 July 2018 - 19 April 2019

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Reason / purpose for cross-reference:

reference to same study

Qualifier:

according to guideline

Guideline:

EU Method A.1 (Melting / Freezing Temperature)

Version / remarks:

2016

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 102 (Melting point / Melting Range)

Version / remarks:

1995

Deviations:

no

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7200 (Melting Point / Melting Range)

Version / remarks:

1998

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Key result

Melting / freezing pt.:

-73.8 °C

Decomposition:

yes

Decomp. temp.:

> 175 °C

Remarks on result:

other: glass transition is reported as substance has no melting temperature

Two experiments were performed to investigate the melting (and boiling) behaviour of the substance.

 

DSC EXPERIMENT 1

During cooling a glass transition was observed between -70°C and -90°C. During heating a glass transition was observed between -90°C and -50°C. The inflection point of the glass transition is -73.719°C. A broad endothermic effect was observed between 25°C and 175°C directly followed by another endothermic effect. The first endothermic effect was most likely caused by evaporation of impurities. The second endothermic effect was probably caused by reaction and/or decomposition of the test item (see endpoint 4.3).

 

DSC EXPERIMENT 2

In order to investigate the first endothermic effect, in Experiment 2 heating was stopped directly after the first endothermic effect. Similar results as in Experiment 1 were obtained. The inflection point of the glass transition was -73.901°C. After the experiment, the remaining residue in the sample container seemed unchanged. It demonstrated that the first endothermic effect was most likely caused by evaporation of impurities.

 

DATA HANDLING

The glass transition was determined as the mean inflection point of Experiment 1 (-73.719°C) and Experiment 2 (-73.901°C).

Conclusions:

A glass transition temperature of -73.8°C was determined.
The substance has no melting/freezing temperature between 25°C and -90°C.

Data source

Reference

Reference Type:

study report

Title:

Unnamed

Year:

2019

Materials and methods

Test guideline

Test guideline 1

Qualifier:

according to guideline

Guideline:

EU Method A.2 (Boiling Temperature)

Version / remarks:

2016

Deviations:

no

Test guideline 2

Qualifier:

according to guideline

Guideline:

OECD Guideline 103 (Boiling Point)

Version / remarks:

1995

Deviations:

no

Test guideline 3

Qualifier:

according to guideline

Guideline:

EPA OPPTS 830.7220 (Boiling Point / Boiling Range)

Version / remarks:

1996

Deviations:

no

GLP compliance:

yes

Type of method:

differential scanning calorimetry

Test material

Test material information

Constituent 1

Reference substance name:

5-hydroxy-4-propyl-2,5-dihydrofuran-2-one

Cas Number:

78920-10-2

Molecular formula:

C7H10O3

IUPAC Name:

5-hydroxy-4-propyl-2,5-dihydrofuran-2-one

Test material form:

liquid: viscous

Details on test material:

- Appearance: Brown viscous liquid
- Storage condition of test material: At room temperature

Results and discussion

Boiling point

Key result

Decomposition:

yes

Decomp. temp.:

> 175 °C

Remarks on result:

other: boiling point not determinable

Any other information on results incl. tables

Two experiments were performed to investigate the (melting and) boiling behaviour of the substance, of which only Experiment 1 is relevant for the boiling point.

 

DSC EXPERIMENT 1

During cooling a glass transition was observed between -70°C and -90°C. During heating a glass transition was observed between -90°C and -50°C. The inflection point of the glass transition is -73.719°C. A broad endothermic effect was observed between 25°C and 175°C directly followed by another endothermic effect. The first endothermic effect was most likely caused by evaporation of impurities (see endpoint 4.2). The second endothermic effect was probably caused by reaction and/or decomposition of the test item.

After the experiment, a dark orange molten residue remained in the sample container (original colour: brown, more orange like). The change of the colour indicated reaction and/or decomposition of the test item.

CONCLUSION

Reaction and/or decomposition of the test item was observed in the DSC experiments at temperatures of > 175°C (> 448K) and at normal atmospheric pressure (1013.25 hPa). 

Boiling of the test item was not observed below the temperature at which reaction and/or decomposition started. Based on this, the test item has no boiling temperature.

Applicant's summary and conclusion

Conclusions:

Reaction and/or decomposition of the substance was observed in DSC experiments, starting at > 175°C.
The substance has no boiling point.