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EC number: 701-029-8
CAS number: -
A 14d-EC50 of >1000 mg/kg soil (d.w.) was obtained for the test substance for the earthworm Eisenia fetida according to OECD 207.No long-term terrestrial tests have been performed due to the hydrolytic instability of the test substance.
The test substance is covered by the category approach of
methylenediphenyl diisocyanates (MDI). Hence, data of the category
substances can be used to cover this endpoint. A short-term toxicity
study (van der Hoeven et al, 1992), carried out according to OECD 207,
is available for PMDI for the earthworm Eisenia fetida. In this
limit test, a 14d-EC50 of >1000 mg/kg soil (d.w.) was obtained in
artificial soil. The endpoint was based on mortality, weight increase,
behaviour and appearance.
No long-term terrestrial tests on soil macro-organisms are available for
the test substance. Because MDI reacts readily with water to form
predominantly insoluble and inert polyurea (Yakabe et al, 1994),
long-term terrestrial toxicity tests are not appropriate for the
derivation of PNEC values.
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