Adenine

Auto flammability

Link to relevant study record(s)

Reference

Endpoint:

relative self-ignition temperature (solids)

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2018-09-05

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

other: VDI 2263, part 1 1990, test methods for the determination of the safety characteristics of dusts; UN Transport Regulations, Appendix 6, Screening Procedures (Substances which may be liable to spontaneous combustion (Division 4.2))

Deviations:

no

Qualifier:

equivalent or similar to guideline

Guideline:

EU Method A.16 (Relative Self-Ignition Temperature for Solids)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Key result

Remarks on result:

no self-ignition observed up to the melting point

In the investigation of self-ignition in the Grewer Oven for the pure test item an endothermic process was detected starting at approx. 330 °C. After the test, the test item in the wire basket was black. No self-ignition could be observed up to the maximum oven temperature of 400 °C.

Results of the screening test for self-ignition in the Gewer-Oven

Experiment	Onset self- ignition / °C	Maximum temperature / °C	Remarks
Pure test item	--	--

 

Conclusions:

No self-ignition could be observed up to the maximum oven temperature of 400 °C.

Executive summary:

A study was conducted equivalent to Regulation (EC) No 440/2008 Part A, A.16 andaccording to VDI 2263, sheet 1.The self-ignition behavior of the test item was determined in the oven according to VDI 2263, sheet 1. For this purpose, the test item was filled in a small wire basket of a volume of 8 cm³ and this wire-basket was placed into the oven. In this oven, the self-ignition behavior of five samples can be determined simultaneously. An additional basket was filled with a reference material (graphite). In the investigation of self-ignition in the Grewer Oven for the pure test item an endothermic process was detected starting at approx. 330 °C. No self-ignition could be observed up to the maximum oven temperature of 400 °C. As the test conditions are quite similar to the method A.1, it was concluded that the results are transferable and no other result would be obtained by a study in accordance with Regulation (EC) No 440/2008 Part A, A.16.

Description of key information

No self-ignition could be observed up to the maximum oven temperature of 400 °C.

Additional information

A study was conducted equivalent to Regulation (EC) No 440/2008 Part A, A.16 andaccording to VDI 2263, sheet 1.The self-ignition behavior of the test item was determined in the oven according to VDI 2263, sheet 1. For this purpose, the test item was filled in a small wire basket of a volume of 8 cm³ and this wire-basket was placed into the oven. In this oven, the self-ignition behavior of five samples can be determined simultaneously. An additional basket was filled with a reference material (graphite). In the investigation of self-ignition in the Grewer Oven for the pure test item an endothermic process was detected starting at approx. 330 °C. No self-ignition could be observed up to the maximum oven temperature of 400 °C. As the test conditions are quite similar to the method A.1, it was concluded that the results are transferable and no other result would be obtained by a study in accordance with Regulation (EC) No 440/2008 Part A, A.16 (reference 4.12 -1).