Registration Dossier
Registration Dossier
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EC number: 263-503-6 | CAS number: 62314-25-4
Endpoint summary
Administrative data
Description of key information
2017 LLNA pre-test: The observations in the OECD 429 LLNA pretests are indicative of the substances being corrosive.
Scores of =/> 3 were observed at concentrations 50, 25 and 10%
Ear swelling was greater than 25% at 25 and 50%
Body weight loss (>5%) was observed possibly indicative of systemic toxicity.
The main argument for not continuing with the main LLNA studies is the interpretation of the study director with regard to eschar formation at all concentrations tested on day 6.
Based on this observation, and in light of experience with the substance it was decided to apply a precautionary labelling of Corrosive 1C to Hydroxypropyl, 2-, trimethylammonium formate.
Key value for chemical safety assessment
Skin sensitisation
Endpoint conclusion
- Endpoint conclusion:
- no study available
Justification for classification or non-classification
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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