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Administrative data

Description of key information

An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 1-[(2-hydroxyethyl)thio]propan-2-ol is not expected to induce skin sensitisation.

Key value for chemical safety assessment

Skin sensitisation

Link to relevant study records
Reference
Endpoint:
skin sensitisation, other
Type of information:
other: expert assessment
Adequacy of study:
key study
Study period:
August 11, 2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
Principles of method if other than guideline:
Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
GLP compliance:
no
Type of study:
other: Assessment based on QSAR predictions supported by reliable experimental data on analogous substances
Key result
Parameter:
other: skin sensitisation
Remarks on result:
other: 1-[(2-hydroxyethyl)thio]propan-2-ol is not expected to induce skin sensitisation

see attached report

Interpretation of results:
GHS criteria not met
Conclusions:
1-[(2-hydroxyethyl)thio]propan-2-ol is not expected to induce skin sensitisation.
Executive summary:

An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 1-[(2-hydroxyethyl)thio]propan-2-ol is not expected to induce skin sensitisation.

Endpoint conclusion
Endpoint conclusion:
no adverse effect observed (not sensitising)

Justification for classification or non-classification

An assessment was performed based on QSAR predictions supported by reliable experimental data on analogous substances. It concluded that 1-[(2-hydroxyethyl)thio]propan-2-ol did not meet the criteria for classification according to Regulation (EC) No.1272/2008.