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Environmental fate & pathways

Adsorption / desorption

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Reference
Endpoint:
adsorption / desorption, other
Type of information:
other: Expert assessment
Adequacy of study:
key study
Study period:
August 10, 2017
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: An assessment was performed based on the composition (organic non-ionic) and Kow partition coefficient of 1-[(2-hydroxyethyl)thio]propan-2-ol.
Qualifier:
no guideline required
Principles of method if other than guideline:
An assessment was performed based on the composition (organic non-ionic) and Kow partition coefficient of 1-[(2-hydroxyethyl)thio]propan-2-ol.
Key result
Remarks on result:
not measured/tested
Key result
Remarks on result:
not measured/tested

1-[(2-hydroxyethyl)thio]propan-2-ol has a predicted value of log Kow of -0.20, which is below 3. The registration substance is, therefore, expected to have a low potential for adsorption and soil sorption (Koc) was not estimated.

Validity criteria fulfilled:
not applicable
Conclusions:
An expert assessment was undertaken using available literature and an existing KOWWIN V1.68 QSAR prediction for Kow for 1-[(2-hydroxyethyl)thio]propan-2-ol. The soil adsorption (Koc) coefficient for 1-[(2-hydroxyethyl)thio]propan-2-ol was not calculated due to the registration substance having a low potential for adsorption, which was inferred from a log Kow value of -0.02 that is below 3.
Executive summary:

To determine the soil adsorption coefficient (Koc) of 1-[(2-hydroxyethyl)thio]propan-2-ol, a literature search was conducted that identified suitable information and data relating to the substance. A KOWWIN V1.68 QSAR prediction rendered a log Kow value of -0.20, and based on the composition of 1-[(2-hydroxyethyl)thio]propan-2-ol, it is possible that soil sorption can be estimated from the octanol-water partition coefficient (Kow). A substance is regarded by SETAC (1993): Guidance Document on Sediment Toxicity Tests and Bioassays for Freshwater and Marine Environments as having the potential for adsorption if its log10 Koc or log10 Kow is 3. As 1-[(2-hydroxyethyl)thio]propan-2-ol has a log Kow of -0.20 that is below 3, the substance is expected to have a low potential for adsorption and, therefore, additional adsorption-desorption data is not required under REACH Annex VIII. Any sorption of 1-[(2-hydroxyethyl)thio]propan-2-ol] to soil or sediment will be negligible.

Description of key information

To determine the soil adsorption coefficient (Koc) of 1-[(2-hydroxyethyl)thio]propan-2-ol, a literature search was conducted that identified suitable information and data relating to the substance. A KOWWIN V1.68 QSAR prediction rendered a Kow value of -0.20, and based on the composition of 1-[(2-hydroxyethyl)thio]propan-2-ol, it is possible that soil sorption can be estimated from the octanol-water partition coefficient (Kow). A substance is regarded by SETAC (1993): Guidance Document on Sediment Toxicity Tests and Bioassays for Freshwater and Marine Environments as having the potential for adsorption if its log10 Koc or log10 Kow is >/= 3. As 1-[(2-hydroxyethyl)thio]propan-2-ol has a log Kow of -0.20 that is below 3, the substance is expected to have a low potential for adsorption and, therefore, additional adsorption-desorption data is not required under REACH Annex VIII and IX. Any sorption of 1-[(2-hydroxyethyl)thio]propan-2-ol] to soil or sediment will be negligible.

Key value for chemical safety assessment

Additional information

The decision not to estimate adsorption-desorption for Koc following an expert assessment was based on a predicted log Kow = -0.02, which infers a low potential adsorption, and is supported by SETAC (1993) and REACH Annex VIII and IX. This conclusion was the result of sound weight of evidence and it has subsequently been assigned a reliability of 2 (reliable with restrictions).