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EC number: 214-987-2
CAS number: 1241-94-7
In the key study for skin irritation, three rabbits (strain and sex not
reported) were given dermal applications of the test material
2-ethylhexyl diphenyl phosphate. The reaction was reported as slightly
irritating. It is considered that the irritant potential of 2-ethylhexyl
diphenyl phosphate may be low and, therefore, in addition, it is
considered unlikely that 2 -ethylhexyl diphenyl phosphate possesses any
A supporting study was available in which human volunteer subjects were
exposed to Santicizer 141 under occlusion. Sancticizer 141 was capable
of eliciting visible skin changes consistent with the criteria deemed
characteristic of a moderately severe primary irritant. However, as no
test guideline has been followed and a deviant scoring system has been
used in this skin test on 200 human volunteer subjects, an appropriate
interpretation of the results cannot be made, and the information
provided is too limited to draw a confident conclusion.
In the key study for eye irritation, conducted in accordance with a
Draize design, 2 -ethylhexyl diphenyl phosphate was applied undiluted to
the eyes of three rabbits of unspecified strain. It was noted that
slight irritation of the eye was found. It is considered that the
irritant potential of 2-ethylhexyl diphenyl phosphate may be low and,
therefore, in addition, it is considered unlikely that 2-ethylhexyl
diphenyl phosphate possesses any corrosive properties.
Based on the available data, no conclusion can be drawn considering the
classification for skin and eye irritation.
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