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Ecotoxicological information

Short-term toxicity to fish

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Reference
Endpoint:
short-term toxicity to fish
Type of information:
read-across from supporting substance (structural analogue or surrogate)
Adequacy of study:
key study
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: The analogue with EC number 309-928-3 (Ultramarine Blue) shares the same functional group with the substance EC number 701-186-2 (Ultramarine Violet) and the results can be extrapolated to Ultramarine Violet.
Justification for type of information:
REPORTING FORMAT FOR THE ANALOGUE APPROACH
1. HYPOTHESIS FOR THE ANALOGUE APPROACH:The analogue approach covers the substance Ultramarine Blue (CAS 57455-37-5) and the substance Ultramarine Violet (CAS 12769-96-9).The analogue Ultramarine Blue shares the same functional group with the substance Ultramarine Violet. Therefore, they are expected to be toxicologically equivalent.
2. SOURCE AND TARGET CHEMICAL(S) (INCLUDING INFORMATION ON PURITY AND IMPURITIES)Ultramarine blue, C.I. Pigment blue 29: CAS number: 57455-37-5, EC name: Silicic acid, aluminum sodium salt, sulfurized, EC number: 309-928-3 Ultramarine Violet, C.I. Pigment Violet 15: CAS number: 12769-96-9, EC name: sodium aluminosilicate violet, EC number: 701-186-1. No relevant impurities.
3. ANALOGUE APPROACH JUSTIFICATIONT: he analogue approach covers the substance Ultramarine Blue (CAS 57455-37-5) and the substance Ultramarine Violet (CAS 12769-96-9).The analogue Ultramarine Blue shares the same functional group with the substance Ultramarine Violet. Therefore, they are expected to be toxicologically equivalent.
4. DATA MATRIX (Please, see attached document "Reporting Format for the analogue approach")
Reason / purpose:
read-across source
Principles of method if other than guideline:
Read-across approach from published data (method OECD Guideline 203) on the analogue EC number 309-928-3 (Reporting format for the analogue approach is attached). Please, see CSR appendix I.
GLP compliance:
yes
Key result
Duration:
96 h
Dose descriptor:
LC50
Effect conc.:
>= 90 mg/L
Nominal / measured:
nominal
Conc. based on:
test mat.
Basis for effect:
mortality

The analogue approach covers the substance Ultramarine Blue (CAS 57455-37-5) and the substance Ultramarine Violet (CAS 12769-96-9).

 

The analogue Ultramarine Blue shares the same functional group with the substance Ultramarine Violet. Therefore, they are expected to be toxicologically equivalent.

Based on the experimental results obtained with the analogue, the read-across approach is applied and the LC50 (96 h) for the substance Ultramarine Violet is considered to be >90 mg/L.

Validity criteria fulfilled:
not applicable
Conclusions:
Based on the experimental results obtained with the analogue, the read-across approach is applied and the LC50 (96 h) for the substance Ultramarine Violet is considered to be >90 mg/L.
Executive summary:

Based on the experimental results obtained with the analogue, the read-across approach is applied and the LC50 (96 h) for the substance Ultramarine Violet is considered to be >90 mg/L.

Description of key information

Read-across from analogue: key study according to OECD Test Guideline 203. The result was as follows: LC50 (96h) > 90 mg/L

Key value for chemical safety assessment

Additional information