Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

The registered substance is hydrolytically stable at pH from 5 to 12 but unstable at pH lower than 5. The registered substance is a macrocyclic compound containing three potentially acid sensitive functionalities:

- The epoxide function of a trisubtituted double bond: in acidic conditions and already at pH 5, the epoxide could open up generating an alcohol and a tertiary carbocation (stabilized intermediate) which could then be intercepted by water to form an alcohol. Globally the epoxide has been transformed to a diol.

- The two trisubstituted double bonds in the molecule: in acidic media an hydration reaction could take place and would lead to tertiary alcohol.

As a conclusion, the registered substance in acidic media will hydrolyze to give poly-hydroxylated product.

Additional information