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Toxicological information

Direct observations: clinical cases, poisoning incidents and other

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Administrative data

Endpoint:
direct observations: clinical cases, poisoning incidents and other
Type of information:
experimental study
Adequacy of study:
weight of evidence
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Adopted according to EU risk assessment report, Cas No. 26447-40-5, methylenediphenyl diisocyanate (MDI), volume 59 (public available peer reviewed source)

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994
Report Date:
1994

Materials and methods

Study type:
clinical case study
Endpoint addressed:
eye irritation
Test guideline
Qualifier:
no guideline required
GLP compliance:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent
Type:
Constituent
Details on test material:
- Name of test material (as cited in study report): 4,4'-MDI (Rock glue)
- Analytical purity: not reported

Method

Type of population:
occupational
Subjects:
- Number of subjects exposed: no data
Route of exposure:
ocular
Reason of exposure:
unintentional, occupational
Exposure assessment:
not specified

Results and discussion

Results of examinations:
symptoms of eye irritation were reported.

Applicant's summary and conclusion