Registration Dossier
Registration Dossier
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EC number: 426-730-3 | CAS number: 123439-82-7
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- calculation (if not (Q)SAR)
- Remarks:
- Migrated phrase: estimated by calculation
- Adequacy of study:
- key study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: Calculation based on good quality experimental data. Limited reporting detail.
- Qualifier:
- according to guideline
- Guideline:
- EU Method A.8 (Partition Coefficient)
- Version / remarks:
- (of Directive 92/69/EEC)
- Deviations:
- yes
- Remarks:
- Reporting detail limited (e.g. missing test item description, GLP compliance).
- GLP compliance:
- not specified
- Type of method:
- other: calculation from solubility data.
- Partition coefficient type:
- octanol-water
- Analytical method:
- other: not applicable
- Type:
- log Pow
- Partition coefficient:
- < -2.3
- Temp.:
- 25 °C
- pH:
- 7
- Remarks on result:
- other: Since no test was perfomed, standard pH and temperature have been assumed
- Details on results:
- The aqueous solubility of the test substance is approximately 18 g/L (Petrovic, 1998b). Its solubility in n-octanol was found to be below 0.1 g/L in a preliminary test. Therefore the approximate partition coefficient is < 0.006, and the log Pow is < -2.3.
- Conclusions:
- The partition coefficient (octanol/water) of tetraamineplatinum(II) hydrogencarbonate was calculated to be < -2.3.
- Executive summary:
Direct measurement of the partition coefficient (octanol/water) of tetraammineplatinum(II) hydrogencarbonate was not possible. Based on the solubilities of the test substance in water and n-octanol, the partition coefficient was calculated to be < -2.3.
Reference
Description of key information
The partition coefficient (octanol/water) of tetraamineplatinum(II) hydrogencarbonate was calculated to be < -2.3 (Petrovic, 1998a)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- -2.3
Additional information
The aqueous solubility of the test substance is approximately 18 g/L (Petrovic, 1998b). Its solubility in n-octanol was found to be below 0.1 g/L in a preliminary test. Therefore the approximate partition coefficient is < 0.006, and the log Pow is < -2.3 (Petrovic, 1998a).
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