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Long-term toxicity to fish

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Description of key information

No chronic toxic effects to fish up to the limit of water solubility (< 1 mg/L) is expected, however a further long term toxicity test to aquatic invertebrates for CAS 85566-26-9 is planned

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Additional information

The chemical safety assessment according to Annex I of Regulation (EC) No. 1907/2006 does not indicate the need to investigate further the long-term toxicity to fish. Thus, in accordance to Annex IX, column 2 no further long-term toxicity testing to fish is proposed. The available experimental studies on aquatic toxicity for all members of the polyol esters category and in particular those which were chosen as suitable read across for fatty acids, coco, di-and triesters with trimethylolpropane (CAS 85566-29-6) show that on all three trophic levels no acute toxic effects up to the water solubility occur. An experimental study for long-term toxicity to aquatic invertebrates for fatty acids, coco, di-and triesters with trimethylolpropane (CAS 85566-29-6) is planned. As there was no sign that fish are the most sensitive species in the short-term tests, one can expected that a long-term test with fish will not generate different results than the planned long-term test with Daphnia. Hence due to animal welfare reasons and to avoid unnecessary vertebrate tests, no further long-term test with fish is proposed for fatty acids, coco, di-and triesters with trimethylolpropane (CAS 85566-29-6). The available data on the long term toxicity of aquatic invertebrates does not reveal adverse effects to daphnids.