Aluminium tridiethylphosphinate

Short-term toxicity to fish

Link to relevant study record(s)

Reference

Endpoint:

short-term toxicity to fish

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1998

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method C.1 (Acute Toxicity for Fish)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 203 (Fish, Acute Toxicity Test)

Deviations:

no

GLP compliance:

yes

Analytical monitoring:

yes

Vehicle:

no

Test organisms (species):

Danio rerio (previous name: Brachydanio rerio)

Test type:

static

Water media type:

freshwater

Limit test:

yes

Total exposure duration:

96 h

Hardness:

2.1 - 2.5 mmol Ca2+ + Mg2+/l

Test temperature:

21.1 - 21.8 °C;

pH:

7.7 - 7.7

Dissolved oxygen:

6.7 - 9.0 mg/l

Reference substance (positive control):

no

Duration:

24 h

Dose descriptor:

LC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Duration:

48 h

Dose descriptor:

LC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Duration:

72 h

Dose descriptor:

LC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Duration:

96 h

Dose descriptor:

LC0

Effect conc.:

100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Remarks on result:

other: No lethality was determined up to solubility limit;

Duration:

96 h

Dose descriptor:

LC50

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Duration:

96 h

Dose descriptor:

LC100

Effect conc.:

> 100 mg/L

Nominal / measured:

nominal

Conc. based on:

test mat.

Basis for effect:

mortality (fish)

Validity criteria fulfilled:

yes

Conclusions:

under the conditions of the this test the LC50 of the test substance after 96 hours was > 100 mg/L nominal and is above the solubility limit of the test substance in the test water.

Executive summary:

The test substance was tested in danio rerio over 96 hours in a static system. The concentrations tested were 100 mg/L and a negative control (0 mg/L). Before insertion of the test organism the test concentrations were stirred for 24 hours to ensure that the limit of solubility of the test substance in water was reached.

The tested concentration showed a light turbidity. Particulate matters were observed on the water surface and the bottom of the test vessel. The substance concentration was determined in the 100 mg/L group. Because of low water solubility the values decreased from 18.7 % of the theoretical value at study start to 6.8 – 7.6 % during exposure and at study end. The analytical determination included dissolved and dispersed undissolved parts of the test substance. The lethality values given in this report are based on nominal concentrations and mean measured concentrations

 

The LC 50 was above the solubility limit of the test substance in the test water.

 

LC 50 > 100 mg/L nominal

LC50 > 11 mg/L measured

Description of key information

The test substance was tested in danio rerio over 96 hours in a static system. The concentrations tested were 100 mg/L and a negative control (0 mg/L). Before insertion of the test organism the test concentrations were stirred for 24 hours to ensure that the limit of solubility of the test substance in water was reached.

The tested concentration showed a light turbidity. Particulate matters were observed on the water surface and the bottom of the test vessel. The substance concentration was determined in the 100 mg/L group. Because of low water solubility the values decreased from 18.7 % of the theoretical value at study start to 6.8 – 7.6 % during exposure and at study end. The analytical determination included dissolved and dispersed undissolved parts of the test substance. The lethality values given in this report are based on nominal concentrations and mean measured concentrations

 

The LC 50 was above the solubility limit of the test substance in the test water.

 

LC 50 > 100 mg/L nominal

LC50 > 11 mg/L measured