Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 239-555-0 | CAS number: 15520-05-5
Endpoint summary
Administrative data
Key value for chemical safety assessment
Genetic toxicity in vitro
Description of key information
Endpoint conclusion
- Endpoint conclusion:
- no adverse effect observed (negative)
Additional information
It can be stated that in the bacterial reverse mutation assay (Ames test) the test item did not cause gene mutations by base pair changes or frameshifts in the genome of the tester strains used.
Therefore, Genamin 3920 is considered to be non-mutagenic in this bacterial reverse mutation assay.
In an in vitro cell gene mutagenicity test the test item is considered to be non-mutagenic in the HPRT locus using V79 cells of the Chinese Hamster.
In a micronucleus assay in the mouse the test item did not induce structural and/or numerical chromosomal damage in the immature erythrocytes of the mouse.
Therefore, the test item is considered to be non-mutagenic with respect to clastogenicity and/or aneugenicity in the Mammalian Erythrocyte Micronucleus Test.
Justification for selection of genetic toxicity endpoint
The study in mammalian cells in vitro was selected
Justification for classification or non-classification
No classification
The test item did not cause mutagenic effects in bacteria as well in mammalian cells in vitro as well as in vivo.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
