Registration Dossier
Registration Dossier
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EC number: 700-316-5 | CAS number: 1155405-88-1
Endpoint summary
Administrative data
Key value for chemical safety assessment
Additional information
Tri-C18-22 (even numbered)-alkyl 2-hydroxypropane-1,2,3-tricarboxylate is not mutagenic in mouse lymphoma L5178Y cells, in either the absence or the presence of S9 mix, when tested to the maximum practicable concentration of 1000 µg/mL.
In addition data are available for a structurally related substance Tri (hexyl, octyl, decyl) citrate with the only difference in the shorter carbon chain length of the ester groups. Due to the structural similarity of the test substance compared to the submission substance the available data can be used for read-across. The test substance did not cause mutagenic effects towards bacteria in a standard Ames test and did not induce structuralchromosomal aberrations in the V79 Chinese hamster cell line.
Endpoint Conclusion: No adverse effect observed (negative)
Justification for classification or non-classification
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