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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Physical & Chemical properties

Dissociation constant

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Administrative data

Link to relevant study record(s)

Reference
Endpoint:
dissociation constant
Type of information:
experimental study
Adequacy of study:
key study
Study period:
2012-12-06
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
guideline study with acceptable restrictions
Qualifier:
according to guideline
Guideline:
OECD Guideline 112 (Dissociation Constants in Water)
GLP compliance:
no
Dissociating properties:
yes
pKa:
ca. 7.6
Temp.:
20 °C
Remarks on result:
other: It is not possible to separately determine the pka1 and pka2 values for this substance in water.
Conclusions:
The dissociation constant is determined to 7.6 at 20 °C. It is not possible to separately determine the pka1 and pka2 values for this substance in water.
Executive summary:

The dissociation constant is determined to 7.6 at 20 °C. It is not possible to separately determine the pka1 and pka2 values for this substance in water.

Description of key information

The dissociation constant is determined to 7.6 at 20 °C. It is not possible to separately determine the pka1 and pka2 values for this substance in water. In a supporting study the pKa values are  predicted to 9.98 and 10.16 for the etherdiamine and 4.77 for the acetate. This at a temperature of 25 °C.

Key value for chemical safety assessment

pKa at 20°C:
7.6

Additional information