Registration Dossier

Data platform availability banner - registered substances factsheets

Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
experimental study
Adequacy of study:
other information
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: Only secondary literature.

Data source

Reference
Reference Type:
secondary source
Title:
No information
Author:
Moiseenok AG et al.
Year:
1979
Bibliographic source:
Khim Farm Zh 13: 22; cited in: BIBRA Toxicity Profile Pantolactone, 1995

Materials and methods

GLP compliance:
not specified

Test material

Constituent 1
Chemical structure
Reference substance name:
α-hydroxy-β,β-dimethyl-γ-butyrolactone
EC Number:
209-963-3
EC Name:
α-hydroxy-β,β-dimethyl-γ-butyrolactone
Cas Number:
599-04-2
Molecular formula:
C6H10O3
IUPAC Name:
(3R)-dihydro-3-hydroxy-4,4-dimethyl-2(3H)-furanone

Test animals

Species:
mouse
Strain:
not specified
Sex:
not specified

Administration / exposure

Route of administration:
intraperitoneal
Vehicle:
not specified
Doses:
no data given
No. of animals per sex per dose:
no data given
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
600 mg/kg bw
Mortality:
no data given
Clinical signs:
no data given
Body weight:
no data given
Gross pathology:
no data given

Applicant's summary and conclusion