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EC number: 203-266-8 | CAS number: 105-06-6
Endpoint summary
Administrative data
Description of key information
Biodegradation in water
Biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance1,4-Bis(ethenyl)benzene (CAS no. 105-06-6) (from authoritative database (J-CHECK, 2018) and secondary source). Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance 1,4-Bis(ethenyl)benzene was determined to be 0 and 3% by BOD and GC parameter in 28 days. Thus, based on percentage degradation, 1,4-Bis(ethenyl)benzene is considered to be not readily biodegradable in nature.
Biodegradation in water and sediment
Estimation Programs Interface (2018) prediction model was run to predict the half-life in water and sediment for the test compound 1,4-Bis(ethenyl)benzene (CAS No. 105 -06 -6). If released in to the environment, 18.4% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of 1,4-Bis(ethenyl)benzene in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of 1,4-Bis(ethenyl)benzene in sediment is estimated to be 135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.852%), indicates that 1,4-Bis(ethenyl)benzene is not persistent in sediment.
Biodegradation in soil
The half-life period of 1,4-Bis(ethenyl)benzene (CAS No. 105 -06 -6) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (2018). If released into the environment, 80.2% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of 1,4-Bis(ethenyl)benzene in soil is estimated to be 30 days (720 hrs). Based on this half-life value of 1,4-Bis(ethenyl)benzene, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low / high.
Additional information
Biodegradation in water
Experimental study and predicted data for the target compound 1,4-Bis(ethenyl)benzene(CAS No. 105-06-6) and various supporting studies for its structurally similar read across substance were reviewed for the biodegradation end point which are summarized as below:
In an experimental key study from authoritative database (J-CHECK, 2018) and secondary source, biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of test substance1,4-Bis(ethenyl)benzene (CAS no. 105-06-6). Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance 1,4-Bis(ethenyl)benzene was determined to be 0 and 3% by BOD and GC parameter in 28 days. Thus, based on percentage degradation, 1,4-Bis(ethenyl)benzene is considered to be not readily biodegradable in nature.
In a prediction using the Estimation Programs Interface Suite (2018), the biodegradation potential of the test compound 1,4-Bis(ethenyl)benzene (CAS no. 105 -06 -6) in the presence of mixed populations of environmental microorganisms was estimated. The biodegradability of the substance was calculated using seven different models such as Linear Model, Non-Linear Model, Ultimate Biodegradation Timeframe, Primary Biodegradation Timeframe, MITI Linear Model, MITI Non-Linear Model and Anaerobic Model (called as Biowin 1-7, respectively) of the BIOWIN v4.10 software. The results indicate that chemical 1,4-Bis(ethenyl)benzene is expected to be not readily biodegradable.
For the test chemical from authoritative databases (2018),biodegradation study was conducted for 28 days for evaluating the percentage biodegradability of test substance. The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I) under aerobic conditions. Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to be 0, 1 and 4% by BOD, TOC removal and HPLC parameter in 28 days. Thus, based on percentage degradation, test chemical is considered to be not readily biodegradable in nature.
In a supporting study from authoritative databases (J-CHECK, 2018 and EnviChem, 2014) for the test item,biodegradation experiment was conducted for 28 days for evaluating the percentage biodegradability of test substance. The study was performed according to OECD Guideline 301 C (Ready Biodegradability: Modified MITI Test (I). Activated sludge was used as a test inoculums for the study. Concentration of inoculum i.e, sludge used was 30 mg/l and initial test substance conc. used in the study was 100 mg/l, respectively. The percentage degradation of test substance was determined to be 2 and 0% by BOD and HPLC parameter in 28 days. Thus, based on percentage degradation, test chemical is considered to be not readily biodegradable in nature.
On the basis of above results for target chemical1,4-Bis(ethenyl)benzene(from authoritative database, secondary source and modelling database, 2017), it can be concluded that the test substance 11,4-Bis(ethenyl)benzenecan be expected to be not readily biodegradable in nature.
Biodegradation in water and sediment
Estimation Programs Interface (2018) prediction model was run to predict the half-life in water and sediment for the test compound 1,4-Bis(ethenyl)benzene (CAS No. 105 -06 -6). If released in to the environment, 18.4% of the chemical will partition into water according to the Mackay fugacity model level III and the half-life period of 1,4-Bis(ethenyl)benzene in water is estimated to be 15 days (360 hrs). The half-life (15 days estimated by EPI suite) indicates that the chemical is not persistent in water and the exposure risk to aquatic animals is moderate to low whereas the half-life period of 1,4-Bis(ethenyl)benzene in sediment is estimated to be 135 days (3240 hrs). However, as the percentage release of test chemical into the sediment is less than 1% (i.e, reported as 0.852%), indicates that 1,4-Bis(ethenyl)benzene is not persistent in sediment.
Biodegradation in soil
The half-life period of 1,4-Bis(ethenyl)benzene (CAS No. 105 -06 -6) in soil was estimated using Level III Fugacity Model by EPI Suite version 4.1 estimation database (2018). If released into the environment, 80.2% of the chemical will partition into soil according to the Mackay fugacity model level III. The half-life period of 1,4-Bis(ethenyl)benzene in soil is estimated to be 30 days (720 hrs). Based on this half-life value of 1,4-Bis(ethenyl)benzene, it is concluded that the chemical is not persistent in the soil environment and the exposure risk to soil dwelling animals is moderate to low / high.
On the basis of available information, the test substance 1,4-Bis(ethenyl)benzene can be considered to be not readily biodegradable in nature.
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