Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Environmental fate & pathways

Endpoint summary

Administrative data

Description of key information

Additional information

Two tests were performed to assess the biodegradability of Creatinine. The first methode used was that described in Part C.4-B of the EC Commission Directive 92/69/EEC and in the OECD Guideline 301 E. The second was according to the German Guideline DIN EN ISO 9888 which is similiar to OECD 302 B (Zahn-Wellens-Test).

In the first test Creatinine (with a nominal concentration of 40 mg DOC/L) was degraded by 96.1 % after 28 days of incubation at 22 +/- 0.6 °C. Under the conditions of the second test 93 % degradation could be observed after 11 days. Also the biodegradation occured within a 10-d window according to the Guideline and therefore Creatinine is regarded as readily biodegradable.