Registration Dossier
Registration Dossier
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EC number: 203-079-1 | CAS number: 103-09-3
Acute Toxicity: inhalation
Administrative data
- Endpoint:
- acute toxicity: inhalation
- Type of information:
- experimental study
- Adequacy of study:
- other information
- Reliability:
- 3 (not reliable)
- Rationale for reliability incl. deficiencies:
- other: Documentation insufficient for assessment (inconsistent results)
Data source
Reference
- Reference Type:
- publication
- Title:
- The place of the range finding test in the industrial toxicology laboratory.
- Author:
- Smyth Jr HF, Carpenter CP
- Year:
- 1 944
- Bibliographic source:
- J. Ind Hyg. Tocicol. 26, 269-273.
Materials and methods
- Principles of method if other than guideline:
- Inhalation hazard test (IHT) to assess the toxicity of a saturated vapour atmosphere.
- GLP compliance:
- no
- Test type:
- other: inhalation hazard test (IHT)
Test material
- Reference substance name:
- 2-ethylhexyl acetate
- EC Number:
- 203-079-1
- EC Name:
- 2-ethylhexyl acetate
- Cas Number:
- 103-09-3
- Molecular formula:
- C10H20O2
- IUPAC Name:
- 2-ethylhexyl acetate
- Details on test material:
- 2-ethylhexyl acetate, no data on purity
Constituent 1
Test animals
- Species:
- rat
- Strain:
- other: albino
- Sex:
- male
Administration / exposure
- Duration of exposure:
- 15 min
- Concentrations:
- saturated vapor
- No. of animals per sex per dose:
- 6
- Control animals:
- no
Results and discussion
Effect levels
- Sex:
- male
- Dose descriptor:
- other: IHT
- Exp. duration:
- 15 min
- Remarks on result:
- other: Following the described methods, 0/6 animals died after 15 min exposure and 6/6 animals died after 30 min exposure to a saturated vapour atmosphere of 2-EHAc.
Any other information on results incl. tables
Concentrated vapor inhalation by rats maximum for no death: 15 min. Deaths occured for exposures longer than 15 min, the next longer exposure period tested was 30 min according to the method.
Applicant's summary and conclusion
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
