Tin sulphate

Short-term toxicity to aquatic invertebrates

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

key study

Study period:

1972

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: no glp, no guideline a available (older than guideline and glp)

Qualifier:

equivalent or similar to guideline

Guideline:

OECD Guideline 202 (Daphnia sp. Acute Immobilisation Test)

Deviations:

not applicable

Principles of method if other than guideline:

For acute tests, 10 daphnids 12 +/- 12 hr old were placed in dublicate test chambers and subjected to the test condidions. Tests were run both with and without food additions as the food changed the values. Complete immobilisation or death was the endpoint. Time: 48h

GLP compliance:

no

Analytical monitoring:

yes

Vehicle:

no

Test organisms (species):

Daphnia magna

Test type:

static

Water media type:

freshwater

Limit test:

no

Total exposure duration:

48 h

Duration:

48 h

Dose descriptor:

LC50

Effect conc.:

55 mg/L

Nominal / measured:

meas. (initial)

Conc. based on:

dissolved

Basis for effect:

mobility

Remarks on result:

other: value for Sn^{2+}

Validity criteria fulfilled:

yes

Conclusions:

LD50(daphnia, 48h)=55mg Sn / L = 99.5 mg SnSO_4 / L

Reference 2

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

1996

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: no glp, no methode, citated by RIVM

Justification for type of information:

Justification for read across: stannous sulphate and stannous chloride are the salts from strong acids (here: hydrochloric and sulfuric acid) wiith Sn(II). In water there is a complete dissoziation in the Sn(II) and the corresponding acid.
In the study water phase the concentration of chloride and sulfate from natural sources is dimension granter than from the test item. So the chloride and the sulfate is insignifican. For adverse effects only the Sn(II) is responsible

Qualifier:

no guideline available

Principles of method if other than guideline:

primary source:
El-Nady FE, Atta MM. 1996. Toxicity and biaoccumulation of heavy metals to some marine
biota from the Egyptian coastal waters. J Environ Sci Health A31: 1529-1545.

GLP compliance:

not specified

Analytical monitoring:

yes

Test organisms (species):

Idotea balthica basteri

Test type:

static

Water media type:

saltwater

Total exposure duration:

106 h

Duration:

106 h

Dose descriptor:

EC50

Effect conc.:

95 mg/L

Nominal / measured:

meas. (initial)

Conc. based on:

dissolved

Remarks:

Sn

Basis for effect:

mortality

Validity criteria fulfilled:

not specified

Conclusions:

EC50(106h)=95 mg/L

Reference 3

Endpoint:

short-term toxicity to aquatic invertebrates

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

1989

Reliability:

2 (reliable with restrictions)

Rationale for reliability incl. deficiencies:

other: no glp, no methode, citated by RIVM

Justification for type of information:

Justification for read across: stannous sulphate and stannous chloride are the salts from strong acids (here: hydrochloric and sulfuric acid) wiith Sn(II). In water there is a complete dissoziation in the Sn(II) and the corresponding acid.
In the study water phase the concentration of chloride and sulfate from natural sources is dimension granter than from the test item. So the chloride and the sulfate is insignificant. For adverse effects only the Sn(II) is responsible

Qualifier:

no guideline available

Principles of method if other than guideline:

primary source: Khangarot BS, Ray PK. 1989a. Investigation of correlation between physicochemical
properties of metals and their toxicity to the water flea Daphnia magna Straus. Ecotoxicol
Environ Saf 18: 109-120.

Analytical monitoring:

not specified

Vehicle:

not specified

Test organisms (species):

Daphnia magna

Test type:

static

Water media type:

freshwater

Total exposure duration:

48 h

Duration:

48 h

Dose descriptor:

EC50

Effect conc.:

22 mg/L

Nominal / measured:

meas. (initial)

Conc. based on:

dissolved

Remarks:

Sn

Basis for effect:

other: immobilisation

Validity criteria fulfilled:

not specified

Conclusions:

EC50(48h)=22mg/L

Description of key information

Key study: Daphnia magna, LD50(daphnia, 48h)=55 mg Sn / L = 99.5 mg SnSO_4 / L

Supporting study: Daphnia magna, EC50(48h)=22 mg/L

Supporting study: Idotea balthica basteri, saltwater, EC50(106h)=95 mg/L

The lowest value with a guideline species has been chosen for as value for fresh water for Risk Assessment.

The data for a salt wtarer specied has been chosen for value salt water for Risk Assessment.

Key value for chemical safety assessment

Fresh water invertebrates

Fresh water invertebrates

Dose descriptor:

EC50

Effect concentration:

22 mg/L

Marine water invertebrates

Marine water invertebrates

Dose descriptor:

EC50

Effect concentration:

95 mg/L