Registration Dossier
Registration Dossier
Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.
The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.
Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice.
EC number: 696-026-0 | CAS number: 1395383-69-3
Biodegradation in water: screening tests
Administrative data
Link to relevant study record(s)
Description of key information
Ready Biodegradability of bis(2,3-epoxypropyl)cyclohexane-1,2-dicarboxylate in a Manometric Respirometry Test
Key value for chemical safety assessment
- Biodegradation in water:
- inherently biodegradable
Additional information
In first study, the substance was tested for its ready biodegradability in the CO2 Evolution Test (Modified Sturm Test) at ca. 42 mg / 2L, corresponding to approx 12 mg TOC / L. The relative degradation values calculated from the measurement of the CO2 formation during the test period of 28 days revealed no significant degradation (4.9% in bottle A and 2.6% in bottle B). The substance was found not readily biodegradable.The toxicity test showed that there is no inhibition of the degradation of sodium acetate by the test substance. Therefore, bis(2,3 -epoxypropyl)cyclohexane-1,2 -can be considered to be inherently biodegradable.
In a second study, the ready biodegradability was tested in a Manometric Respirometry Test. The criterion for ready biodegradability under the conditions of a manometric respirometry test is the 10-day window, describing the period between reaching at least 10% degradation and 60% degradation. This period should not exceed 10 days.
The mean biodegradation after 28 days of bis(2,3 -epoxypropyl)cyclohexane-1,2 -dicarboxylate was 53% (ThODNH4) and 94% after 60 days; the 10 day window criterion was not passed.
Whilst bis(2,3 -epoxypropyl)cyclohexane-1,2 -dicarboxylate cannot be considered to be readily biodegradable under the strict terms and conditions of OECD Guideline No. 301F, the evidence of aerobic degradation (94%) that did not plateau before the end of the 60-day indicate the potential for complete mineralisation in the environment.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
Reproduction or further distribution of this information may be subject to copyright protection. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner.
