Registration Dossier
Registration Dossier
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EC number: 482-100-8 | CAS number: -
Bioaccumulation: aquatic / sediment
Administrative data
Link to relevant study record(s)
Description of key information
QSAR determinations of the BCF for the compoents are < 500 L/kg
Key value for chemical safety assessment
Additional information
In accordance with Annex IX column 2 of the REACH Regulation, a study for bioaccumulation does not need to be conducted if the substance has a low potential for bioaccumulation. The experimentally derived Log Pow value for the substance has been identified as > 9.4. ECHA Guidance on Information requirements and chemical safety assessment Chapter R11: PBT assessment (page 28) on determination of bioaccumulation potential states: at very high log Kow (>6), a decreasing relationship between BCF and Log Pow is observed. Apart from experimental errors in the determination of BCF values for these very hydrophobic chemicals, reduced uptake due to the increasing molecular size may play a role as well. Moreover, the experimental determination of log Kow for very hydrophobic chemicals is normally also very uncertain due to experimental difficulties. Ideally the results of several model predictions should be considered. QSAR calculations of BCF for the components determined that the BCF < 500 L/kg. Therefore the substance is not considered to bioaccumulate.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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