Registration Dossier

Administrative data

Endpoint:
two-generation reproductive toxicity
Type of information:
experimental study
Adequacy of study:
key study

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994
Report Date:
1994

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
OECD Guideline 416 (Two-Generation Reproduction Toxicity Study)
Deviations:
no
Limit test:
no

Test material

Reference
Name:
Unnamed
Type:
Constituent

Test animals

Species:
rat
Strain:
Sprague-Dawley
Sex:
male/female

Administration / exposure

Route of administration:
oral: drinking water

Results and discussion

Results: P0 (first parental animals)

Effect levels (P0)

open allclose all
Dose descriptor:
other:
Effect level:
50 mg/kg bw/day
Sex:
male/female
Basis for effect level:
other:
Remarks on result:
other:
Dose descriptor:
other:
Effect level:
1 000 mg/kg bw/day
Sex:
male/female
Remarks on result:
other:
Dose descriptor:
other:
Effect level:
250 mg/kg bw/day
Sex:
male/female
Remarks on result:
other:

Overall reproductive toxicity

Reproductive effects observed:
not specified

Applicant's summary and conclusion