Registration Dossier

Administrative data

Endpoint:
acute toxicity: dermal
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Study period:
1994
Reliability:
2 (reliable with restrictions)
Rationale for reliability incl. deficiencies:
other: Not GLP and not enough details to consider it a full described study. It is scientifically valid to assess the endpoint

Data source

Reference
Reference Type:
study report
Title:
Unnamed
Year:
1994

Materials and methods

Test guideline
Qualifier:
according to
Guideline:
EPA OPPTS 870.1200 (Acute Dermal Toxicity)
Deviations:
no
GLP compliance:
not specified
Test type:
fixed dose procedure
Limit test:
yes

Test material

Reference
Name:
Unnamed
Type:
Constituent
Details on test material:
Purity: 99.6%

Test animals

Species:
rabbit
Strain:
not specified
Sex:
not specified

Administration / exposure

Doses:
2000 mg/Kg
Control animals:
not specified

Results and discussion

Effect levels
Sex:
not specified
Dose descriptor:
LD50
Effect level:
> 2 000 mg/kg bw
Based on:
not specified

Applicant's summary and conclusion

Interpretation of results:
not classified
Remarks:
Migrated information Criteria used for interpretation of results: EU
Conclusions:
The substance was not considered to be an acute dermal toxic
Executive summary:

LD50 has been tested in a fixed dose test at 2000 mg/kg/bw on rabbit with fatty acids C6 -C12 methyl esters following EPA OPPTS 870.1200 with no sigh of toxicity