Tin

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

08.04.2009 - 29.05.2009

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Deviations:

no

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

Deviations:

no

GLP compliance:

yes (incl. QA statement)

Type of method:

column elution method

Water solubility:

< 4 µg/L

Temp.:

20 °C

pH:

>= 6.5 - <= 7.7

Details on results:

The limit of detection of the analytical method was estimated to be approximately 4 µg/L.

The calibration was found to be linear over the range 0 to 100 µg/L of standard tin solutions with a regression coefficient of 0.9967. The limit of detection of the analytical method was estimated to be approximately 4 µg/L. This was the lowest standard concentration that produced a response above background levels. An acceptable mean recovery value of 84 % was determined from a series of fortified control solutions prepared at levels approximately 5 and 10 times the analytical limit of detction. Blank control samples were analysed and confirmed the absence of significant interference.

Table 1: Measurements of water solubility at 20 °C

Column flow rate = 0.4 mL/minute

Sample	Concentration	pH
	(µg/L)
0.4A	< 4	6.9
0.4B	< 4	6.9
0.4C	< 4	6.6
0.4D	< 4	6.7
0.4E	< 4	7.0
0.4F	< 4	6.6

Column flow rate = 0.2 mL/minute

Sample	Concentration	pH
	(µg/L)
0.2A	< 4	6.5
0.2B	< 4	7.5
0.2C	< 4	7.7
0.2D	< 4	7.6
0.2E	< 4	7.1

Conclusions:

Interpretation of results: insoluble (< 0.1 mg/L)
Tin metal (15 - 28 µm) is considered to be insoluble in water.

Executive summary:

Tin metal (15 - 28 µm) was determined to have a water solubility value of less than 4 µg/L at 20 ºC, which was the limit of detection for the analytical method, and is considered to be insoluble in water.

Reference 2

Endpoint:

water solubility

Type of information:

other: review article

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

secondary literature

Remarks:

The reference does not give sufficient experimental details and refers to secondary literature (highly credible review article)

Principles of method if other than guideline:

No data available

GLP compliance:

not specified

Type of method:

other: not reported

Remarks on result:

other:

Remarks:

Insoluble

Conclusions:

Interpretation of results: insoluble (< 0.1 mg/L)
The substance is reported to be insoluble in water.

Executive summary:

The substance is considered insoluble in water.

Reference 3

Endpoint:

water solubility

Type of information:

other: Non-peer reviewed publically available data

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

secondary literature

Remarks:

The reference does not give sufficient experimental details and refers to secondary literature.

Principles of method if other than guideline:

No data available

GLP compliance:

not specified

Type of method:

other: Not reported

Remarks on result:

other: Tin metal is insoluble in hot or cold water. Data source stated as Metallo-chimique N.V. Beerse. no further data on results available.

Conclusions:

Interpretation of results: insoluble (< 0.1 mg/L)
The substance was reported as insoluble in water.

Executive summary:

The substance is considered insoluble in water.

Reference 4

Endpoint:

water solubility

Type of information:

other: Safety data sheet

Adequacy of study:

supporting study

Reliability:

4 (not assignable)

Rationale for reliability incl. deficiencies:

abstract

Remarks:

The reference does not give sufficient experimental details and is listed only in short abstract

Principles of method if other than guideline:

No data available

GLP compliance:

not specified

Type of method:

other: not reported

Remarks on result:

other: The substance was reported to be insoluble in water, no further data on results are available.

Conclusions:

Interpretation of results: insoluble (< 0.1 mg/L)
The substance is reported as insoluble in water.

Executive summary:

The substance is considered insoluble in water.

Description of key information

One GLP study is available which was performed in line with OCED guideline 105. One handbook reference is also available, for which legitimate access is possible, along with an IUCLID dataset and MSDS for which access is not possible (nor required)

Key value for chemical safety assessment

Water solubility:

0.004 mg/L

at the temperature of:

20 °C

Additional information

Data in the public domain suggest that tin is insoluble. This is confirmed by a study performed in line with OCED guideline 105 and carried out to GLP which produced a water solubility value of 4 µg/L at 20 ºC. This value was the limit of detection of the analytical method. The water solubility of tin is anticipated to be much lower in reality.