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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Toxicological information

Acute Toxicity: other routes

Currently viewing:

Administrative data

Endpoint:
acute toxicity: other routes
Type of information:
migrated information: read-across based on grouping of substances (category approach)
Adequacy of study:
disregarded due to major methodological deficiencies
Reliability:
4 (not assignable)
Rationale for reliability incl. deficiencies:
other: This information was obtained from the public IUCLID 2000 CD-ROM. The original report has not been reviewed further. Assessment of data quality to current OECD standards is not possible and the study has therefore been assigned Reliability 4.

Data source

Referenceopen allclose all

Reference Type:
review article or handbook
Title:
The Merck Index - Encyclopedia of Chemicals, Drugs and Biologicals
Author:
Budavari S ed
Year:
1989
Bibliographic source:
11th edn. ISBN 0-911910-28-X. Rahway, NJ, U.S.A. Merck and Co. 2240 p
Reference Type:
review article or handbook
Title:
The Merck Index. An encyclopedia of Chemicals, Drugs, and Biologicals
Author:
O'Neil MJ, Heckelman PE, Koch CB, Roman KJ eds
Year:
2006
Bibliographic source:
14th edn. ISBN: 978-0-911910-00-1. Whitehouse Station, NJ, U.S.A. Merck and Co. 1740 p
Reference Type:
review article or handbook
Title:
The Merck Index. An encyclopedia of Chemicals, Drugs, and Biologicals
Author:
Budaravi S, O'Neil MJ, Smith A, Heckelman PE, Kinneary JF eds
Year:
1996
Bibliographic source:
12th edn. ISBN 0911910-12-3. Whitehouse Station, NJ, U.S.A. Merck and Co. 1741 p

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
Iron trichloride
EC Number:
231-729-4
EC Name:
Iron trichloride
Cas Number:
7705-08-0
Molecular formula:
FeCl3
IUPAC Name:
iron(3+) trichloride

Test animals

Species:
mouse

Administration / exposure

Route of administration:
intravenous

Results and discussion

Effect levelsopen allclose all
Dose descriptor:
LD50
Effect level:
49 mg/kg bw
Based on:
test mat.
Remarks:
FeCl3
Dose descriptor:
LD50
Effect level:
17 mg/kg bw
Based on:
element
Remarks:
Fe

Applicant's summary and conclusion