Registration Dossier
Registration Dossier
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EC number: 212-782-2 | CAS number: 868-77-9
Partition coefficient
Administrative data
Link to relevant study record(s)
- Endpoint:
- partition coefficient
- Type of information:
- experimental study
- Adequacy of study:
- key study
- Reliability:
- 1 (reliable without restriction)
- Rationale for reliability incl. deficiencies:
- guideline study
- Remarks:
- Report in japanese language available
- Qualifier:
- according to guideline
- Guideline:
- OECD Guideline 107 (Partition Coefficient (n-octanol / water), Shake Flask Method)
- GLP compliance:
- yes
- Type of method:
- shake-flask method to: flask method
- Partition coefficient type:
- octanol-water
- Specific details on test material used for the study:
- - Purity: 98.2 %
- Analytical method:
- high-performance liquid chromatography
- Key result
- Type:
- log Pow
- Partition coefficient:
- 0.42
- Temp.:
- 25 °C
- pH:
- >= 5.9 - <= 6.1
- Conclusions:
- The log Pow was determined to be 0.42 at 25 deg C.
- Executive summary:
The octanol-water partition coefficient of 2-hydroxyethyl methacrylate was tested in a shake flask test acc. OECD 107 under GLP conditions. The log Pow was determined to be 0.42 at 25 °C.
Reference
Description of key information
The log Kow of HEMA is 0.42 (OECD Guideline 107 / shake flask method)
Key value for chemical safety assessment
- Log Kow (Log Pow):
- 0.42
- at the temperature of:
- 25 °C
Additional information
Additional information of a log Pow measured by shake flask method (Tanii, 1982) is available and reported to be 0.47 at room temperature. The log Pow calculated with EPI Suite v4.11 is 0.30.
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