Registration Dossier
Registration Dossier
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EC number: 200-902-6 | CAS number: 75-79-6
Toxicity to aquatic algae and cyanobacteria
Administrative data
Link to relevant study record(s)
Description of key information
There are no test data for the substance. However a 72 EC50 value of >3.6 mg/L and NOEC of ≥3.6 mg/L (geometric mean measured concentrations) have been determined for the effects of a read-across substance, Trimethoxy(methyl)silane (CAS 1185-55-3), on growth rate of Pseudokirchnerella subcapitata. The same results expressed in terms of nominal concentrations were >120 mg/L and ≥120 mg/L respectively. It is likely that the test organisms were predominantly exposed to the hydrolysis products of the substance. A reliable result for a second read-across substance (Triethoxy(methyl)silane; CAS Number 2031-67-6) is also available but the EC50 is higher.
Key value for chemical safety assessment
Additional information
No test data for toxicity to aquatic algae and cyanobacteria are available for trichloro(methyl)silane. However a study of toxicity to algae is available for the related substance Trimethoxy(methyl)silane. Trichloro(methyl)silane (CAS 75-79-6) and Trimethoxy(methyl)silane (CAS 1185 -55 -3) both hydrolyse to methylsilanetriol. The hydrolysis half-lives of Trichloro(methyl)silane and Trimethoxy(methyl)silane indicate that, under conditions relevant to ecotoxicity assessment, both will hydrolyse to methylsilanetriol in the course of the tests. The other hydrolysis products are hydrogen chloride and methanol, respectively; the properties of these substances are well characterised. Methanol is non-toxic to the environment and it is considered unlikely that it’s presence significantly affected the results of the test performed with trimethoxy(methyl)silane. Effects of hydrogen chloride on aquatic organisms are limited to those that result from changes to pH in unbuffered media.
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