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Partition coefficient

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Reference
Endpoint:
partition coefficient
Type of information:
experimental study
Adequacy of study:
key study
Study period:
20/11/1996 - 04/12/1996
Reliability:
1 (reliable without restriction)
Rationale for reliability incl. deficiencies:
other: The study is considered to be a reliability 1 as it has been conducted according to OECD TG 117 (HPLC) and in compliance with GLP.
Qualifier:
according to
Guideline:
OECD Guideline 117 (Partition Coefficient (n-octanol / water), HPLC Method)
GLP compliance:
yes
Type of method:
HPLC method
Partition coefficient type:
octanol-water
Analytical method:
high-performance liquid chromatography
Key result
Type:
log Pow
Partition coefficient:
5.6
Temp.:
30 °C
Remarks on result:
other: pH is not considered relevant as the substance has no ionisable groups.
Key result
Type:
log Pow
Partition coefficient:
5.7
Temp.:
30 °C
Remarks on result:
other: pH is not considered relevant as the substance has no ionisable groups
Details on results:
The partition coefficients n-octanol/water of OTNE, corresponding to the two peaks that appear on the chromatogram, are:
log Pow = 5.6
log Pow = 5.7

The pH is assessed not to be critical based on the absence of acidic and basic structural features of OTNE in its molecular structure.

Conclusions:
The partition coefficient of OTNE has been determined as log P = 5.65 at 30°C under OECD TG 117 (HPLC) in compliance with GLP.

Executive summary:

The partition coefficient of OTNE has been determined as log P = 5.65 at 30°C under OECD TG 117 (HPLC).

Description of key information

The partition coefficient of OTNE has been determined as log P = 5.65 at 30°C under OECD TG 117 (HPLC).

Key value for chemical safety assessment

Log Kow (Log Pow):
5.65
at the temperature of:
30 °C

Additional information