Registration Dossier
Registration Dossier
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EC number: 210-478-4 | CAS number: 616-38-6
Basic toxicokinetics
Administrative data
- Endpoint:
- basic toxicokinetics
- Type of information:
- experimental study
- Adequacy of study:
- supporting study
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- secondary literature
- Remarks:
- Unpublished data cited from a peer reviewed publication
Data source
Reference
- Reference Type:
- secondary source
- Title:
- Enzymatic hydrolysis of carbomethoxy compounds
- Author:
- Rauenbusch E
- Year:
- 1 974
- Bibliographic source:
- Unpublished report from Bayer AG, Wuppertal, Germany. Cited in: JEFCA Monograph for Dimethyldicarbonate (DMDC). WHO, Geneva
Materials and methods
Test material
- Reference substance name:
- Dimethyl carbonate
- EC Number:
- 210-478-4
- EC Name:
- Dimethyl carbonate
- Cas Number:
- 616-38-6
- Molecular formula:
- C3H6O3
- IUPAC Name:
- dimethyl carbonate
Constituent 1
Results and discussion
Applicant's summary and conclusion
- Conclusions:
- The incubation of dimethyl carbonate with liver or kidney homogenates of porcine or human origin resulted in hydrolytic decomposition of the substance. Further study details were not reported.
- Executive summary:
The incubation of dimethyl carbonate with liver or kidney homogenates of porcine or human origin resulted in hydrolytic decomposition of the substance. Further details of this study were not reported.
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