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Ecotoxicological information

Toxicity to aquatic algae and cyanobacteria

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Administrative data

Link to relevant study record(s)

Description of key information

Acute value 72h-ErC50: The lowest effect concentration of all valid tests (OECD Guideline 201) was obtained with Fully saturated TEA-Esterquat with the alga Scenedesmus subspicatus. The 72h-ErC50 (72h-EbC50) value is 2.14 (1.28) mg/L. Long-term value 72h-ErC10: five comparable, valid and relevant studies (OECD Guideline 201) are considered in a Weight of Evidence (WoE) approach. For the WoE approach, the geometric mean of the five 72h-ErC10 values was calculated to be 72h-ErC10 = 1.48 mg/L.

Key value for chemical safety assessment

EC50 for freshwater algae:
2.14 mg/L
EC10 or NOEC for freshwater algae:
1.48 mg/L

Additional information

Long-term value 72h-EC10/NOEC: As long-term effect value, instead of the NOEC, the EC10 is used. The current OECD guideline 201, 2011 (No. 58) as well as ECHA Guidance R.10, 2008 (Table R.10-1) as well as ECHA CLP Guidance, Nov. 2012 (4.1.3.1.1) recommend the use of the ErC10 instead of NOEC for classification as well as starting point for PNEC derivation.

For the long-term effect value 72h-ErC10, relevant studies are considered in a Weight of Evidence (WoE) approach: For TEA-EQ (Partially unsaturated, Fully saturated, Oleic acid-based), for the endpoint “Toxicity to aquatic algae and cyanobacteria”, there are five valid and comparable studies for the same taxonomic group available. For each study there is a full endpoint study record (EPR) in the dossier. The 72h-ErC10 values for these studies are: Cognis (2004) 0.68 mg/L, Evonik (1994f) 1.53 mg/L, Evonik Goldschmidt (2005g) 5.09 mg/L, Kao (1993a) 1.26 mg/L, Kao (1993b) 1.26 mg/L. The assessment of these comparable studies showed no study inherent reason for differences in results. All five studies were conducted following guidance OECD201. All five EPR consider for effect calculation a concentration reduction factor to map the decrease of nominal concentration during the test duration. The values for 72h-ErC10 range from 0.68 – 5.09 mg/L. For the WoE approach, the geometric mean of the five 72h-ErC10 values was calculated. According to this WoE approach, for this endpoint the 72h-ErC10 = 1.48 mg/L.

 

Acute value 72h ErC50: The lowest effect concentration of all valid tests is used. The test was made with Fully saturated TEA-Esterquat which inhibited significantly the increase of biomass of the alga Scenedesmus subspicatus in a study conducted according to OECD Guideline 201 (Alga, Growth Inhibition Test). The 72h-ErC50 (72h-EbC50) value is 2.14 (1.28)mg/L.