Reaction products of diphenylamine with nonene, branched

Water solubility

Link to relevant study record(s)

Reference

Reference 1

Endpoint:

water solubility

Remarks:

representative constituent B with CAS number 27177-41-9

Type of information:

experimental study

Adequacy of study:

supporting study

Study period:

2002

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

EU Method A.6 (Water Solubility)

Version / remarks:

Commission Directive EEC92/69, A.6

GLP compliance:

yes (incl. QA statement)

Type of method:

flask method

Key result

Water solubility:

11.3 µg/L

Conc. based on:

test mat. (total fraction)

Incubation duration:

72 h

Temp.:

20 °C

pH:

>= 5.7 - <= 6.2

Remarks on result:

other: mean value of 3 flasks (24,48,72h)

Details on results:

4.4 Discussion
There was some sample to sample variation probably due to the very low level of solubility and the difficulties with clean-up procedures of saturated test solutions at low levels. The sample to sample variation in the results was considered valid for these reasons.
Sponsor information and the chemical structure indicated that the column elution method should have been performed as the solubility was less than lx10-2 g/l. However, due to the physical nature of the test material, it was not possible to use this method; experience has shown that liquid test materials coated onto glass beads cause these beads to adhere together forming a plug within
the column and thus preventing water circulation.

Recovery of analysis of the sample procedure was carried out and proved adequate for the test. Mean recovery 86% / 89%

 

Conclusions:

The water solubility of the test substance was determined to be 11,3 µg/L at 20°C, pH ~6

Reference 2

Endpoint:

water solubility

Type of information:

experimental study

Adequacy of study:

key study

Study period:

2009

Reliability:

1 (reliable without restriction)

Rationale for reliability incl. deficiencies:

guideline study

Qualifier:

according to guideline

Guideline:

OECD Guideline 105 (Water Solubility)

GLP compliance:

no

Type of method:

column elution method

Key result

Water solubility:

< 5 µg/L

Conc. based on:

test mat. (total fraction)

Temp.:

20 °C

pH:

6.1 - 6.2

Conclusions:

The water solubility of the whole test substance was determined to be <5 µg/L at 20°C, pH 6.1

Description of key information

Measured value of the whole substance:

<5 µg/L at 20°C, pH 6.1

 

The estimated values of the representative isomers are as follows:

Structure A= 1.6 E-4 µg/L at 25°C

Structure B= 4.4 µg/L at 25°C

Additional information

The measurement was carried out by column elution method according to OECD Guideline 105.

In addition, the substance is a UVCB thus the water solubility on representative isomers of the registered substance have been generated by calculation using recommended program WSKOW module of software EPI Suite.

With respect to the water solubility of the structure B, an isomer with CAS number 27177-41-9 has been reported a value of 11,3 µg/L in the publication of screening assessments which has released by Canadian goverment. This is referred to the study Lubrizol SPL 525/382, 2002.

Further the water solubility of a homologue substance with CAS number 15721 -78 -5 (Di-octylphenyl, C8) has been reported a value of <52,3 µg/L at 28°C which is referred to ECHA disseminated dossier (DUSLO-Dossier, 2015).