Registration Dossier
Registration Dossier
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EC number: 700-442-0 | CAS number: 73573-88-3
Skin sensitisation
Administrative data
- Endpoint:
- skin sensitisation
- Remarks:
- other: DEREK Nexus software
- Type of information:
- other: DEREK Nexus software
- Adequacy of study:
- weight of evidence
- Reliability:
- 2 (reliable with restrictions)
- Rationale for reliability incl. deficiencies:
- other: not OECD test used
Data source
Reference
- Reference Type:
- other:
- Title:
- Unnamed
- Year:
- 2 012
- Report date:
- 2012
Materials and methods
Test guideline
- Qualifier:
- no guideline followed
- Guideline:
- other: DEREK Nexus software
- GLP compliance:
- no
- Type of study:
- not specified
Test material
- Reference substance name:
- (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl(2S)-2-methylbutanoate
- EC Number:
- 700-442-0
- Cas Number:
- 73573-88-3
- Molecular formula:
- C23H34O5
- IUPAC Name:
- (1S,7S,8S,8aR)-8-{2-[(2R,4R)-4-hydroxy-6-oxotetrahydro-2H-pyran-2-yl]ethyl}-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl(2S)-2-methylbutanoate
Constituent 1
Results and discussion
Any other information on results incl. tables
Computational toxicology summary was prepared by DEREK Nexus version 2.0.2 software, and the result for skin sensitisation is equivocal.
Applicant's summary and conclusion
- Interpretation of results:
- sensitising
- Remarks:
- Migrated information Skin Sens 1 H 317 Criteria used for interpretation of results: expert judgment
- Conclusions:
- Computational toxicology summary was prepared by DEREK Nexus version 2.0.2 software, and the result for skin sensitisation is equivocal.
- Executive summary:
Computational toxicology summary was prepared by DEREK Nexus version 2.0.2 software, and the result for skin sensitisation is equivocal.
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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