Registration Dossier
Registration Dossier
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EC number: 255-449-7 | CAS number: 41583-09-9
Toxicity to soil microorganisms
Administrative data
Link to relevant study record(s)
Description of key information
Key value for chemical safety assessment
Additional information
No data with the target substance were available. A weight of evidence approach with the read across source substance melamine (CAS 108-78-1) is applied.
A study (Hauck, 1964) with the read across source substance melamine (CAS 108 -78 -1) was performed. Please refer section 13 for the read across justification. Melamine solutions (ca. 490 mg melamine/ kg soil) perfusing through silty clay loam soil slightly delayed the rate of nitrate formation from added ammonium by ca. 2 days.
According to REACH Annex IX 9.4 studies investigating the effects on terrestrial organisms do not need to be conducted if direct and indirect exposure to the soil compartment is unlikely. The Mackay Modelling shows that the soil is no target compartment for melamine. Melamine is distributed only to the water (95 %) and to the air (5 %). Furthermore, melamine has a low potential to absorb to soil. Based on the low n-octanol/water partition coefficient also the adsorption to soil or sediment is expected to be low (Koc < 21 L/kg; Log Koc < 1.3).
Information on Registered Substances comes from registration dossiers which have been assigned a registration number. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). This information has not been reviewed or verified by the Agency or any other authority. The content is subject to change without prior notice.
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