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EC number: 270-128-1
CAS number: 68411-46-1
No inhibitory or toxic effects of the UVCB
substance and similar substances were determined by acute tests on fish
and activated sludge, respectively. However, slight toxicity was
observed in acute test with Daphnia. Thus, the UVCB substance is
considered to be slightly acutely toxic to Daphnia.
However, there is evidence that the
substituted diphenylamines as C8 mono- and C8 di-alkylated
diphenylamines are not acutely toxic to Daphnia. Furthermore, dose
response relationship was observed in the Daphnia test but the effects
did not correspond to the measured concentrations of the main
study on the effects of the UVCB substance on Daphnia reproduction is
available. Adverse effects were observed, however, the EC10
(reproduction) was determined to be 1.69mg/L.
data on algae show that the EC50 growth rate is > 100mg/l and the NOEC
is > 10mg/L for UVCB substance EC 270 -128 -1
No effects in fish was observed in acute
studies. Furthermore, in a BCF study with a substance similar to one
constituent of the UVCB substance (CAS 27177-41-9) no adverse effects in
fish were observed throughout the exposure period of 42 days and the
elimination period of 42 days. No long-term adverse effects to fish are
expected. Therefore, and for reasons of animal welfare, a long-term
toxicity study in fish is not proposed.
No toxicity in the solubility range of the
substituted diphenylamines was observed in the available acute and
chronic aquatic toxicity data.
Furthermore, it could
be shown that the observed effects in the Daphnia studies with the UVCB
Substance CAS68411-46-1 were concentration dependent. The representative
components of the uvcb substance with the highest bioaccumulation
potential are poorly water soluble. It is doubtful that these
constituents have caused these effects because there were tested at
saturation concentration also at different loading rates.
Toxic effects to sediment organisms were
observed in test according to OECD 225. The EC10-values for biomass and
reproduction were determined to be 81.0 and 44.6 mg/kg sediment dry
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