Registration Dossier

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Please be aware that this old REACH registration data factsheet is no longer maintained; it remains frozen as of 19th May 2023.

The new ECHA CHEM database has been released by ECHA, and it now contains all REACH registration data. There are more details on the transition of ECHA's published data to ECHA CHEM here.

Diss Factsheets

Administrative data

Endpoint:
sub-chronic toxicity: oral
Type of information:
read-across based on grouping of substances (category approach)
Adequacy of study:
key study
Justification for type of information:
For justification of read across see category justification attached to category object.

Data source

Materials and methods

Test material

Constituent 1
Chemical structure
Reference substance name:
2-(2-(2-butoxyethoxy)ethoxy)ethanol
EC Number:
205-592-6
EC Name:
2-(2-(2-butoxyethoxy)ethoxy)ethanol
Cas Number:
143-22-6
Molecular formula:
C10H22O4
IUPAC Name:
2-[2-(2-butoxyethoxy)ethoxy]ethanol
Constituent 2
Reference substance name:
205-22-6
IUPAC Name:
205-22-6
Constituent 3
Reference substance name:
2-(2-(2-butoxy)ethoxy)ethanol
IUPAC Name:
2-(2-(2-butoxy)ethoxy)ethanol
Details on test material:
Name of test material (as cited in study report): 2-(2-(2-butoxy)ethoxy)ethanol
Analytical purity: purity 79.5%

Results and discussion

Effect levels

Dose descriptor:
NOAEL
Effect level:
500 mg/kg bw/day (nominal)
Based on:
test mat.
Sex:
male/female
Remarks on result:
other: based on a weighted average consideration of the results for this substance based on other substances within the category. Result corrected for molecular weight differences.

Target system / organ toxicity

Critical effects observed:
not specified

Applicant's summary and conclusion